49 Results for "

SNAP-tag

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "SNAP-tag" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-131015
CAS No.: 2080306-25-6
Purity:  99.28%
Research Areas:  

Others

HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .
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Cat. No.: HY-W017776
CAS No.: 674799-96-3
Synonyms: SNAP-NH2
BG-NH2 is a pharmaceutical intermediate. BG-NH2 is suitable for synthesizing fluorescent SNAP tag substrates to label RNA .
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Cat. No.: HY-151645
CAS No.: 1104822-07-2
Purity:  99.32%
Target:  

ADC Linkers

Research Areas:  

Others

Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
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Cat. No.: HY-131028
Purity:  ≥95.0%
Synonyms: JF646 TFA
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 646/664 nm).
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Cat. No.: HY-151646
Purity:  99.59%
Synonyms: Alkyne-PEG5-BG
Target:  

ADC Linkers

Research Areas:  

Others

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-136936
CAS No.: 2068027-79-0
Purity:  98.27%
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
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Cat. No.: HY-130736
CAS No.: 1811539-32-8
Synonyms: JF549, SE; JF549, NHS
Janelia Fluor? 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor? 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .
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Cat. No.: HY-139162
CAS No.: 1151762-33-2
Purity:  99.47%
Research Areas:  

Others

BGN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-139163
CAS No.: 2996069-91-9
Purity:  98.16%
Research Areas:  

Others

BGSN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGSN3 are reasonable (IC50=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-148958
CAS No.: 471918-16-8
SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .
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Cat. No.: HY-136937
CAS No.: 2067339-51-7
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-D2965
CAS No.: 1219603-04-9
Synonyms: SPG1
SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
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Cat. No.: HY-175417
Target:  

PROTACs

Research Areas:  

Cancer

VHL-SNAP2-5C is a SNAP-fusion protein PROTAC degrader basing on a self-labeling protein SNAP tag. VHL-SNAP2-5C by endogenous tagging enables the visualization and the selective depletion of a SNAP-fusion protein, such as CLCa andEGFP .
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Cat. No.: HY-D2949
CAS No.: 2836233-28-2
SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
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Cat. No.: HY-D2966
CAS No.: 1928762-04-2
TMR-NO-BG is a hybrid probe (Ex/Em: 557 nm/571 nm). TMR-NO-BG covalently connects the tetramethylrhodamine (TMR) lactone NO sensing unit with the SNAP-tag reactive benzyl guanine (BG) for achieving subcellular-specific nitric oxide (NO) detection .
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Cat. No.: HY-D2994
CAS No.: 2434651-49-5
Synonyms: SNAP-MaP555
SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
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Cat. No.: HY-D2923
CAS No.: 1811539-43-1
PA-JF549-Halo ligand is a covalently linked conjugate comprising the photoactivatable fluorescent dye PA-JF549 and a ligand for the HaloTag protein. PA-JF549-Halo ligand exhibts inherent structural properties and predispose it to localize within mitochondria. PA-JF549-Halo ligand combines the exceptional brightness, photostability, and cell permeability of the JF549 dye with photoactivation capabilities and the high specificity characteristic of HaloTag protein labeling technology. PA-JF549-Halo ligand enables high-quality single-molecule imaging and super-resolution imaging of specific proteins within live cells .
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Cat. No.: HY-D2926
Synonyms: BG-Tz; SNAP-Tetrazine
BG-Tetrazine (BG-Tz; SNAP-Tetrazine) is a SNAP tag substrate that contains a methyl tetrazine group. BG-Tetrazine can specifically covalently label the target protein of the intracellular SNAP-tag fusion. The tetrazine group it carries can rapidly and efficiently undergo a bioorthogonal reaction with functional groups such as trans cyclooctene (TCO), thereby enabling multiple labeling, functionalization or enrichment of proteins. BG-Tetrazine can be applied in click chemistry .
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Cat. No.: HY-D2940
CAS No.: 1418275-29-2
Synonyms: SiR650-BG
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
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Cat. No.: HY-D2944
CAS No.: 1627942-39-5
SNAP-649 is a DY-649P1-labeled SNAP tag fluorescent probe.
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