3 Results for "

SR 57227A

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "SR 57227A" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-102064
CAS No.: 77145-61-0
Purity:  99.86%
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

SR 57227A is a potent, orally active and selective 5-HT3 receptor agonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects .
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Cat. No.: HY-121704
CAS No.: 77145-51-8
Target:  

iGluR

Research Areas:  

Neurological Disease

SR 57227A Free base is a highly selective compound for both peripheral and central 5-HT3 receptors and acts as an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells, demonstrating antidepressant-like effects in rats while reducing isolation-induced aggressive behavior.
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Cat. No.: HY-102064R
CAS No.: 77145-61-0
Research Areas:  

Neurological Disease

SR 57227A (Standard) is the analytical standard of SR 57227A (HY-102064). This product is intended for research and analytical applications. SR 57227A is a potent, orally active and selective 5-HT3 receptor agonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects .
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