77145-51-8
77145-51-8
Chemical Structure
SR 57227A free base
- CAS No.: 77145-51-8
- Formula:C10H14ClN3
- Molecular Weight:211.69
IUPAC Name: 1-(6-chloropyridin-2-yl)piperidin-4-amine
InChIKey: WPVVMKYQOMJPIN-UHFFFAOYSA-N
SMILES: NC1CCN(CC1)C2=NC(Cl)=CC=C2
Biological Activity: SR 57227A Free base is a highly selective compound for both peripheral and central 5-HT3 receptors and acts as an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells, demonstrating antidepressant-like effects in rats while reducing isolation-induced aggressive behavior.
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SR 57227A free base | SR 57227A Free base is a highly selective compound for both peripheral and central 5-HT3 receptors and acts as an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells, demonstrating antidepressant-like effects in rats while reducing isolation-induced aggressive behavior. | |||||||||||||||||||||
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