STAR

By Targets:	Akt (1) AMPK (1) Apoptosis (2) Autophagy (1) Biochemical Assay Reagents (1) Calcium Channel (4) Endogenous Metabolite (5) Environmental Pollutants (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) HBV (1) Herbicide (1) Isotope-Labeled Compounds (1) MDM-2/p53 (1) mTOR (1) Neuropeptide FF Receptor (1) Orphan Nuclear Receptor (1) Parasite (1) PERK (1) PGC-1α (1) PPAR (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) SARS-CoV (4) Small Interfering RNA (siRNA) (5) Smo (1) TNF Receptor (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (4) Endocrinology (4) Infection (3) Inflammation/Immunology (2) Metabolic Disease (4) Neurological Disease (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (3) siRNAs (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0740

4-Methoxybenzaldehyde	Environmental Pollutants Endogenous Metabolite	Metabolic Disease
4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-15483

DY131 3 Publications Verification GSK 9089	Estrogen Receptor/ERR Smo	Endocrinology Cancer
DY131 (GSK 9089) is a potent and selective ERRγ and ERRβ agonist. DY131displays inactive against ERRα, ERα and ERβ . DY131 also inhibits Smo signaling .

HY-12502A

Efonidipine hydrochloride monoethanolate 1 Publications Verification NZ-105 hydrochloride monoethanolate; (±)-Efonidipine hydrochloride monoethanolate	Calcium Channel SARS-CoV	Cardiovascular Disease Neurological Disease Cancer
Efonidipine (NZ-105) hydrochloride monoethanolate is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC₅₀ values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride monoethanolate inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride monoethanolate modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride monoethanolate reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride monoethanolate improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride monoethanolate can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .

HY-W073128

Perfluorotetradecanoic acid PFTeDA	PPAR Apoptosis PGC-1α AMPK Akt mTOR Reactive Oxygen Species (ROS)	Endocrinology
Perfluorotetradecanoic acid (PFTeDA) is an orally active perfluoroalkyl substance. Perfluorotetradecanoic acid directly binds to the ligand-binding domain of purified hPPARγ, with a K_d value of 157.8 μM. Perfluorotetradecanoic acid significantly reduces the activity of the SIRT1/PGC1α and AMPK signaling pathways while stimulating the activity of the AKT1/mTOR signaling pathway. Perfluorotetradecanoic acid significantly upregulates the expression of corticosterone biosynthesis genes. Perfluorotetradecanoic acid increases ROS levels and promotes Apoptosis. Perfluorotetradecanoic acid impairs Leydig cell function and male reproductive endocrine function in adult male rats .

HY-12502

Efonidipine 1 Publications Verification NZ-105; (±)-Efonidipine	Calcium Channel SARS-CoV	Cardiovascular Disease Neurological Disease Cancer
Efonidipine (NZ-105) is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC₅₀ values of 1.8 and 350 nM, respectively. Efonidipine inhibits SARS-CoV-2 main protease. Efonidipine modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine reduces plasma aldosterone levels in vivo. Efonidipine improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .

HY-134462

RJW103	Orphan Nuclear Receptor	Metabolic Disease Cancer
RJW103 is an acid-stable SF-1 (NR5A1) and LRH-1 agonist with pEC₅₀ values of 6.5 and 5.9, respectively. RJW103 activates SF-1- and LRH-1-mediated transcription of endogenous target genes. RJW103 can be used in research on cancer, endocrinology and metabolic diseases, such as adrenocortical tumors .

HY-D2348

ACE	Fluorescent Dye	Infection Others
ACE is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .

HY-W1048851B

4-Arm-PEG10000-Maleimide 4-Arm-PEG10000-Mal	Biochemical Assay Reagents	Others
4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation .

HY-12502B

Efonidipine hydrochloride NZ-105 hydrochloride; (±)-Efonidipine hydrochloride	Calcium Channel SARS-CoV	Cardiovascular Disease Cancer
Efonidipine (NZ-105) hydrochloride is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC₅₀ values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .

HY-Y0740R

4-Methoxybenzaldehyde (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
4-Methoxybenzaldehyde (Standard) is the analytical standard of 4-Methoxybenzaldehyde. This product is intended for research and analytical applications. 4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-P10780

RFRP-3 (mouse) Neuropeptide NPVF (mouse)	Neuropeptide FF Receptor Apoptosis MDM-2/p53 PERK	Endocrinology
RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3β-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development .

HY-RS24627

Star Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Star Rat Pre-designed siRNA Set A contains three designed siRNAs for Star gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Star Rat Pre-designed siRNA Set A Star Rat Pre-designed siRNA Set A

HY-RS13875

STAR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
STAR Human Pre-designed siRNA Set A contains three designed siRNAs for STAR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

STAR Human Pre-designed siRNA Set A STAR Human Pre-designed siRNA Set A

HY-RS18153

Star Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Star Mouse Pre-designed siRNA Set A contains three designed siRNAs for Star gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Star Mouse Pre-designed siRNA Set A Star Mouse Pre-designed siRNA Set A

HY-143656

SH379	Autophagy	Endocrinology
SH379 is the derivative of 2-methylpyrimidine-fused tricyclic diterpene. SH379 is a potent and orally active anti-late-onset hypogonadism agent. SH379 significantly promotes the expression of the key testosterone synthesis-related enzymes StAR and 3β-HSD. SH379 stimulates autophagy through regulating AMPK/mTOR signaling pathway .

HY-161384

WJM-715	Parasite	Infection
WJM-715 is an antimalarial agent with an EC₅₀ of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a K_D of 14 nM .

HY-N12136

1α-Hydroxy-3-deoxypseudoanisatin	Others	Others
1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) is a sesquiterpenoid obtained from star anise (Illicium merrillianum) isolated from the peel .

HY-RS02193

CD163L1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD163L1 Human Pre-designed siRNA Set A contains three designed siRNAs for CD163L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD163L1 Human Pre-designed siRNA Set A CD163L1 Human Pre-designed siRNA Set A

HY-N12102

Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside	HBV	Infection
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside (compound 1) is a lignan with anti-HBC activity. Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside targets HBV surface antigen with IC₅₀s of 0.58 mM (HBsAg) and >2.4 mM (HBeAg). Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside can be isolated from star anise .

HY-RS05921

GUCY2C Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GUCY2C Human Pre-designed siRNA Set A contains three designed siRNAs for GUCY2C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GUCY2C Human Pre-designed siRNA Set A GUCY2C Human Pre-designed siRNA Set A

HY-Y0740S

4-Methoxybenzaldehyde-d1	Endogenous Metabolite	Others
4-Methoxybenzaldehyde-d₁ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-Y0740S1

4-Methoxybenzaldehyde-d3	Endogenous Metabolite	Others
4-Methoxybenzaldehyde-d₃ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-12502AR

Efonidipine hydrochloride monoethanolate (Standard) NZ-105 hydrochloride monoethanolate (Standard); (±)-Efonidipine hydrochloride monoethanolate (Standard)	Reference Standards Calcium Channel SARS-CoV	Cardiovascular Disease
Efonidipine (NZ-105) hydrochloride monoethanolate (Standard) is the analytical standard of Efonidipine hydrochloride monoethanolate (HY-12502AR). This product is intended for research and analytical applications. Efonidipine (NZ-105) hydrochloride monoethanolate is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC₅₀ values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride monoethanolate inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride monoethanolate modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride monoethanolate reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride monoethanolate improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride monoethanolate can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .

HY-W721611

Terbucarb	Herbicide	Others
Terbucarb is a phenylcarbamate herbicide. Terbucarb disrupts the mitotic microtubule organizing centers in plant cells, leading to the formation of multipolar spindles and branched phragmoplasts, thereby inhibiting plant growth. An "anaphase star" pattern induced by Terbucarb is observed in onion root tips. Terbucarb is cytotoxic to isolated rat hepatocytes, inducing cell death accompanied by depletion of intracellular ATP, protein thiols and glutathione .

HY-P992132

Solaprubart STAR-0310	TNF Receptor	Inflammation/Immunology
Solaprubart is a humanized IgG1-κ monoclonal antibody targeting TNFSF4/OX40L. Solaprubart regulates immune homeostasis by blocking the OX40L-OX40 signaling pathway and can be used for the research of autoimmune diseases such as atopic dermatitis .

HY-W750726

7,8,7’,8’-Tetradehydroastaxanthin	Endogenous Metabolite	Others
7,8,7’,8’-Tetradehydroastaxanthin is a glycopeptide isolated from the carotenoid protein of red sea star (Asterias rubens) .

HY-Y0740S2

4-Methoxybenzaldehyde-d2	Isotope-Labeled Compounds	Metabolic Disease
4-Methoxybenzaldehyde-d2 is the deuterium labeled 4-Methoxybenzaldehyde (HY-W041300). 4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

Cat. No.	Product Name

HY-L917

RNA Binding Library	5,619 compounds
RNA is crucial for the regulation of numerous cellular processes and functions. With the in-depth study of disease mechanisms, processes such as RNA expression, splicing, translation, and stability regulation have become new targets for disease intervention. RNA has provided new therapeutic modalities for metabolic diseases, genetic disorders, and cancer patients, resulting in several innovative drugs. MCE R&D team collected small molecules targeting RNA from the PDB, R-BIND, ROBIN, and internal database as the positive dataset, and non-targeting RNA small molecules from ROBIN as the negative dataset. Based on the GeminiMol pre-trained model, we encoded the molecules and calculated over 1700 molecular descriptors using Mordred as inputs for the model. Subsequently, we employed 13 deep learning models to learn from the data. All of which yielded good training results, with AUROCs greater than 0.75. Ultimately, we selected the Finetune model to screen HY-L901P, which exhibited the best classification performance, achieving an AUROC of 0.82 and a prediction accuracy of 0.76. We then applied filtering based on StaR rules (with at least two of the following properties: cLogP ≥ 1.5, Molar Refractivity ≥ 4, Relative Polar Surface Area ≤ 0.3) to obtain a library containing approximately 5,000 small molecule compounds targeting RNA. This library serves as a valuable tool for screening small molecules that interact with RNA.

RNA Binding Library

5,619 compounds

RNA is crucial for the regulation of numerous cellular processes and functions. With the in-depth study of disease mechanisms, processes such as RNA expression, splicing, translation, and stability regulation have become new targets for disease intervention. RNA has provided new therapeutic modalities for metabolic diseases, genetic disorders, and cancer patients, resulting in several innovative drugs.

MCE R&D team collected small molecules targeting RNA from the PDB, R-BIND, ROBIN, and internal database as the positive dataset, and non-targeting RNA small molecules from ROBIN as the negative dataset. Based on the GeminiMol pre-trained model, we encoded the molecules and calculated over 1700 molecular descriptors using Mordred as inputs for the model. Subsequently, we employed 13 deep learning models to learn from the data. All of which yielded good training results, with AUROCs greater than 0.75. Ultimately, we selected the Finetune model to screen HY-L901P, which exhibited the best classification performance, achieving an AUROC of 0.82 and a prediction accuracy of 0.76. We then applied filtering based on StaR rules (with at least two of the following properties: cLogP ≥ 1.5, Molar Refractivity ≥ 4, Relative Polar Surface Area ≤ 0.3) to obtain a library containing approximately 5,000 small molecule compounds targeting RNA. This library serves as a valuable tool for screening small molecules that interact with RNA.

Cat. No.	Product Name	Type

HY-D2348

ACE	Fluorescent Dye
ACE is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .

Cat. No.	Product Name	Type

HY-W1048851B

4-Arm-PEG10000-Maleimide 4-Arm-PEG10000-Mal	Biochemical Assay Reagents
4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation .

Cat. No.	Product Name	Target	Research Area

HY-P10780

RFRP-3 (mouse) Neuropeptide NPVF (mouse)	Neuropeptide FF Receptor Apoptosis MDM-2/p53 PERK	Endocrinology
RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3β-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990931

Navenibart STAR-0215	Inhibitory Antibodies	Inflammation/Immunology
HY-P990931 is an KLKB1-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P992132

Solaprubart STAR-0310	TNF Receptor	Inflammation/Immunology
Solaprubart is a humanized IgG1-κ monoclonal antibody targeting TNFSF4/OX40L. Solaprubart regulates immune homeostasis by blocking the OX40L-OX40 signaling pathway and can be used for the research of autoimmune diseases such as atopic dermatitis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0740

4-Methoxybenzaldehyde	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Illicium verum Hook. f. Illiciaceae Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-Y0740R

4-Methoxybenzaldehyde (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Illicium verum Hook. f. Illiciaceae Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
4-Methoxybenzaldehyde (Standard) is the analytical standard of 4-Methoxybenzaldehyde. This product is intended for research and analytical applications. 4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-N12136

1α-Hydroxy-3-deoxypseudoanisatin	Terpenoids Sesquiterpenes Plants Illicium merrillianum A. C. Smith Schisandraceae Source Classification	Others
1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) is a sesquiterpenoid obtained from star anise (Illicium merrillianum) isolated from the peel .

HY-N12102

Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside	Lignans Phenylpropanoids Plants Schisandraceae Illicium henryi Diels. Source Classification	HBV
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside (compound 1) is a lignan with anti-HBC activity. Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside targets HBV surface antigen with IC₅₀s of 0.58 mM (HBsAg) and >2.4 mM (HBeAg). Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside can be isolated from star anise .

HY-W750726

7,8,7’,8’-Tetradehydroastaxanthin	Natural Products Animals Source Classification	Endogenous Metabolite
7,8,7’,8’-Tetradehydroastaxanthin is a glycopeptide isolated from the carotenoid protein of red sea star (Asterias rubens) .

Species:	Human (8) Mouse (6) Cynomolgus (2) Canine (1)
Tag:	His (13) Avi (6) Myc (1) Fc (4)
Source:	HEK293 (16) CHO (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78741

	GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, Fc) GUCY2C; GUC2C; STAR; STA receptor; hSTAR; GC-C	Mouse	HEK293
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78866

	GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, Fc-Avi) GUCY2C; GUC2C; STAR; STA receptor; hSTAR; GC-C	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, Fc-Avi) is 407 a.a., with molecular weight of 90-110 kDa.

HY-P701282

	FITC-labeled GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) GUCY2C; GUC2C; STAR; STA receptor; hSTAR; GC-C	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. FITC-labeled GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-labeled GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with Fc labeled tag.

HY-P701283

	FITC-labeled GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His) GUCY2C; GUC2C; STAR; STA receptor; hSTAR; GC-C	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. FITC-labeled GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His) is the recombinant human-derived FITC-labeled GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with His labeled tag.

HY-P78742

	GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His) GUCY2C; GUC2C; STAR; STA receptor; hSTAR; GC-C	Mouse	HEK293
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77679

	GUCY2C/Guanylyl cyclase C Protein, Cynomolgus (HEK293, His) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; MUCIL	Cynomolgus	HEK293
	GUCY2C, a guanylyl cyclase, crucially catalyzes cGMP synthesis from GTP. As a receptor for E. coli heat-stable enterotoxin, GUCY2C significantly stimulates cGMP accumulation in mammalian cells, emphasizing its role in mediating responses to specific external stimuli and showcasing intricate regulatory mechanisms in cellular signaling. GUCY2C/Guanylyl cyclase C Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-His labeled tag.

HY-P705193

	GUCY2C/Guanylyl cyclase C Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; MUCIL	Cynomolgus	HEK293

HY-P77680

	GUCY2C/Guanylyl cyclase C Protein, Canine (HEK293, His) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; MUCIL	Canine	HEK293
	GUCY2C, a guanylyl cyclase, crucially catalyzes cGMP synthesis from GTP. As a receptor for E. coli heat-stable enterotoxin, GUCY2C significantly stimulates cGMP accumulation in mammalian cells, emphasizing its role in mediating responses to specific external stimuli and showcasing intricate regulatory mechanisms in cellular signaling. GUCY2C/Guanylyl cyclase C Protein, Canine (HEK293, His) is the recombinant canine-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-His labeled tag.

HY-P704652

	GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293, with C-His labeled tag.

HY-P77943

	GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His-Avi) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P701000

	GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His-Avi) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Mouse	HEK293
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704653

	GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Mouse	CHO
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by CHO, with C-His labeled tag.

HY-P700603

	GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, N-His, C-Myc) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Mouse	HEK293
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, N-His, C-Myc) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.

HY-P700415

	GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, N-His) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, N-His) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P77944

	GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700999

	GUCY2C/Guanylyl cyclase C Protein, Mouse (Biotinylated, HEK293, His-Avi) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Mouse	HEK293
	GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P77942

	GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL	Human	HEK293
	GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-hFc labeled tag.

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Species
Source
Tag
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Cat. No.	Product Name	Chemical Structure

HY-Y0740S

4-Methoxybenzaldehyde-d1

4-Methoxybenzaldehyde-d₁ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-Y0740S1

4-Methoxybenzaldehyde-d3

4-Methoxybenzaldehyde-d₃ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-Y0740S2

4-Methoxybenzaldehyde-d2

4-Methoxybenzaldehyde-d2 is the deuterium labeled 4-Methoxybenzaldehyde (HY-W041300). 4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

Host:	Rabbit (4)
Reactivity:	Human (4) Mouse (2)
Application:	IHC-P (1) ICC/IF (1) IF-Tissue (1) WB (3) IHC-F (1)
Isotype:	IgG (4)
Conjugation:	Non-conjugated (4) Biotin (4)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87618

	StAR Antibody (YA7302)	IHC-P, IHC-F, IF-Tissue	Human
	StAR Antibody (YA7302) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to StAR.

HY-P81192

	StAR Antibody (YA3542) STARD1; Cholesterol trafficker; Luteinizing hormone induced protein; Mitochondrial steroid acute regulatory protein; STAR related lipid transfer (START) domain containing 1; STARD1; START domain containing protein 1; Steroidogenic Acute Regulatory Protein; Steroidogenic acute regulatory protein mitochondrial; STAR_HUMAN.	WB	Human, Mouse
	StAR Antibody (YA3542) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to StAR.

HY-P81192A

	StAR Antibody (YA3542)(PBS only) STARD1; Cholesterol trafficker; Luteinizing hormone induced protein; Mitochondrial steroid acute regulatory protein; STAR related lipid transfer (START) domain containing 1; STARD1; START domain containing protein 1; Steroidogenic Acute Regulatory Protein; Steroidogenic acute regulatory protein mitochondrial; STAR_HUMAN.	WB	Human, Mouse
	StAR Antibody (YA3542) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to StAR.

HY-P86295

	STARD4 Antibody (YA5987) STARD4; STAR-related lipid transfer protein 4 ; START domain-containing protein 4; STARD4;	WB, ICC/IF	Human
	STARD4 Antibody (YA5987) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STARD4.

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Appearance
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SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS24627

Star Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Star Rat Pre-designed siRNA Set A contains three designed siRNAs for Star gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13875

STAR Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
STAR Human Pre-designed siRNA Set A contains three designed siRNAs for STAR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS18153

Star Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Star Mouse Pre-designed siRNA Set A contains three designed siRNAs for Star gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02193

CD163L1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CD163L1 Human Pre-designed siRNA Set A contains three designed siRNAs for CD163L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS05921

GUCY2C Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
GUCY2C Human Pre-designed siRNA Set A contains three designed siRNAs for GUCY2C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Screening Libraries

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