WJM-715
WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C19H22Cl2N4O4S
- Peso molecular:473.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
>40 μM
Compound: 19b; WJM-715
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by Cell Titer-Glo assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by Cell Titer-Glo assay
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[PMID: 38554474] |
In Vitro
WJM-715 improves the aqueous solubility at pH 7.4 to 60 μM and the metabolic stability in rats hepatocytes to 68 μL/min/106cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 473.37
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Fòrmula C19H22Cl2N4O4S
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SMILES
O=S(N1CCOCC1)(C2=C(Cl)C=CC(NC(C)(C)C(NC3=CN=CC(Cl)=C3)=O)=C2)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WJM-715 Related Classifications
HY-161384 Related Classifications
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