2. Autophagy
  3. Autophagy
  4. SH379

SH379 is the derivative of 2-methylpyrimidine-fused tricyclic diterpene. SH379 is a potent and orally active anti-late-onset hypogonadism agent. SH379 significantly promotes the expression of the key testosterone synthesis-related enzymes StAR and 3β-HSD. SH379 stimulates autophagy through regulating AMPK/mTOR signaling pathway.

For research use only. We do not sell to patients.

SH379 Chemical Structure

SH379 Chemical Structure

CAS No. : 2511665-40-8

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SH379 Related Antibodies

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Description

SH379 is the derivative of 2-methylpyrimidine-fused tricyclic diterpene. SH379 is a potent and orally active anti-late-onset hypogonadism agent. SH379 significantly promotes the expression of the key testosterone synthesis-related enzymes StAR and 3β-HSD. SH379 stimulates autophagy through regulating AMPK/mTOR signaling pathway[1].

Molecular Weight

379.50

Formula

C23H29N3O2
CAS No.
SMILES

C[C@@]12C3=CC(OC)=C(C(NC)=O)C=C3CC[C@@]1([H])C(C)(C4=NC(C)=NC=C4C2)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SH379 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SH3792511665-40-8SH 379SH-379Autophagytricyclic diterpeneoralanti-late-onset hypogonadismStAR3β-HSDAMPKmTORautophagyInhibitorinhibitorinhibit

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