1349099-55-3
Chemical Structure
4-Arm-PEG10000-Maleimide
Synonym(s): 4-Arm-PEG10000-Mal
- CAS No.: 1349099-55-3
- Formula:(C2H4O)n(C2H4O)n(C2H4O)n(C2H4O)nC41H52N8O16
- Molecular Weight:10000 (Average)
SMILES: O=C(CCN1C(C=CC1=O)=O)NCCOCCOCC(COCCOCCNC(CCN2C(C=CC2=O)=O)=O)(COCCOCCNC(CCN3C(C=CC3=O)=O)=O)COCCOCCNC(CCN4C(C=CC4=O)=O)=O.[n].[n].[n].[n]
Biological Activity: 4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Arm-PEG10000-Maleimide | 97.0% | 4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation. | ||||||||||||||||||||
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4-Arm-PEG3400-Maleimide | 4-Arm-PEG3400-Maleimide (4-Arm-PEG3400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides. | |||||||||||||||||||||
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4-Arm-PEG5000-Maleimide | 99.31% | 4-Arm-PEG5000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery. | ||||||||||||||||||||
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4-Arm-PEG40000-Maleimide | 4-Arm-PEG40000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery. | |||||||||||||||||||||
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4-Arm-PEG1000-Maleimide | 4-Arm-PEG1000-Maleimide (4-Arm-PEG1000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides. | |||||||||||||||||||||
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4-Arm-PEG20000-Maleimide | 97.0% | 4-Arm-PEG20000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery. | ||||||||||||||||||||
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References
- [1]. Kalinovsky DV, et al. Targeting GD2-Positive Tumor Cells by Pegylated scFv Fragment-Drug Conjugates Carrying Maytansinoids DM1 and DM4. Curr Issues Mol Biol. 2023;45(10):8112-8125. Published 2023 Oct 5. [Content Brief]
- [2]. Vijayamohanan H, et al. Spirothiopyran-based reversibly saturable photoresist. Chemistry of Materials. 2017 Jun 13;29(11):4754-60.
