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Stearidonic acid

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By Targets:	Biochemical Assay Reagents (1) Endogenous Metabolite (1) Lipoxygenase (1)
By Research Areas:	Metabolic Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113120

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Lipoxygenase	Metabolic Disease
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an orally active polyunsaturated fatty acid found in blackcurrant seed oil. Stearidonic acid can inhibit 5-lipoxygenase and reduce leukotriene and 5-HETE synthesis. Stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can be used for the research of metabolic disease .

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents	Others
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

HY-164994

LysoPC (18:4(6Z,9Z,12Z,15Z))	Endogenous Metabolite	Metabolic Disease
LysoPC (18:4(6Z,9Z,12Z,15Z)) is a lysophosphatidylcholine carrying stearidonic acid. LysoPC (18:4(6Z,9Z,12Z,15Z)) crosses the blood retinal barrier via the Mfsd2a transporter .

Cat. No.	Product Name	Type

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Ethyl stearidonate

Biochemical Assay Reagents

6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Lipoxygenase
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an orally active polyunsaturated fatty acid found in blackcurrant seed oil. Stearidonic acid can inhibit 5-lipoxygenase and reduce leukotriene and 5-HETE synthesis. Stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can be used for the research of metabolic disease .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Stearidonic acid

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products