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Succinimide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldose Reductase (1) Bacterial (1) Biochemical Assay Reagents (8) Cyclic GMP-AMP Synthase (2) Drug Derivative (1) Drug Isomer (1) Drug-Linker Conjugates for ADC (3) Fluorescent Dye (2) Isotope-Labeled Compounds (1) Reference Standards (1)
By Research Areas:	Cancer (3) Infection (2) Metabolic Disease (3) Neurological Disease (6)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-79647

Fmoc-OSu N-(Fmoc-oxy)Succinimide	Biochemical Assay Reagents	Others
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-15314

Ranirestat 1 Publications Verification AS-3201	Aldose Reductase	Neurological Disease Metabolic Disease
Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC₅₀s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a K_i of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas .

HY-B1730

Phensuximide 2 Publications Verification	Cyclic GMP-AMP Synthase	Neurological Disease Metabolic Disease
Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal .

HY-41877

*Succinimide* pyrrolidine-2,5-dione	Biochemical Assay Reagents	Others Neurological Disease
Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent .

HY-75200

N-(Benzyloxycarbonyloxy)succinimide	Biochemical Assay Reagents	Others
N-(Benzyloxycarbonyloxy)succinimide is an efficient amino-protecting reagent in organic synthesis, playing an important role in the field of organic synthesis. N-(Benzyloxycarbonyloxy)succinimide is also a neutral ionophore, which significantly improves the performance of erbium ion (Er ³⁺) sensors and provides a practical tool for the rapid detection of erbium ions in the environment and water quality .

HY-P10355

Succinimide-AFK-AMC acetate	Bacterial	Infection
Succinimide-AFK-AMC acetate is a marker for P. aeruginosa protease activity using cultured reference strains .

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dye	Others
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-178275

*Hydrotecan-NH-L-Ala-L-Val-L-Gln(CO-C5-succinimide)-D-glucitol*	Drug-Linker Conjugates for ADC	Cancer
Hydrotecan-NH-L-Ala-L-Val-L-Gln(CO-C5-succinimide)-D-glucitol (Example 9) is a conjugate of the ADC toxic molecule and the linker, where the toxic molecule part is Hydrotecan (HY-164378), and the linker part is Mc-Glu(D-Glucamine)-val-ala (HY-178309) .

HY-148459

ATAC21	Drug-Linker Conjugates for ADC	Cancer
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate .

HY-W160127

N-Hydroxymethyl succinimide N-MethylolSuccinimide	Biochemical Assay Reagents	Others
N-Hydroxymethyl succinimide (N-Methylolsuccinimide) is a promoiety used as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs). N-Hydroxymethyl succinimide enhances the lipophilicity of NSAIDs and reducing the gastrointestinal toxicity of NSAIDs. N-Hydroxymethyl succinimide is promising for research of anti-inflammatory drug delivery system .

HY-41877S

Succinimide-15N	Isotope-Labeled Compounds	Others
Succinimide- ¹⁵N is the ¹⁵N labeled Succinimide. Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent .

HY-174289

*TMTHSI succinimide* NHS ester**	Biochemical Assay Reagents	Others
TMTHSI succinimide NHS ester is a highly efficient cyclic alkyne click reagent. TMTHSI succinimide NHS ester has the primary activity to rapidly undergo strain-promoted cycloaddition reactions with azides. TMTHSI succinimide NHS ester is easily functionalized and can be linked to a variety of small molecules and (peptides, nucleic acids) biologics via a variety of linkers .

HY-W744780

Docosahexaenoic acid N-succinimide	Biochemical Assay Reagents	Others
Docosahexaenoic Acid N-Succinimide is the succinimide analog of Docosahexaenoic Acid. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HY-W097106

(S)-3-N-Cbz-Amino-succinimide	Drug Isomer	Neurological Disease
(S)-3-N-Cbz-Amino-succinimide (Compound 1d) is an antiepileptic agent that can inhibit pentylenetetrazole (PTZ) and maximal electroshock (MES)-induced tonic convulsions in mice .

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dye	Others
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-B1730R

Phensuximide (Standard)	Cyclic GMP-AMP Synthase Reference Standards	Neurological Disease Metabolic Disease
Phensuximide (Standard) is the analytical standard of Phensuximide. This product is intended for research and analytical applications. Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal .

HY-179327

*N-(Hexanoyloxy)succinimide-MMAE*	Drug-Linker Conjugates for ADC	Others
N-(Hexanoyloxy)succinimide-MMAE is a conjugate of the ADC drug toxin molecule and the linker, containing a degradable PEG linker and the toxin molecule MMAE (HY-15162) .

HY-W244412

2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride	Biochemical Assay Reagents	Cancer
2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride is an intermediate of a radionuclide molecular probe targeting the CD4 receptor. 2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride serves as an imaging agent for heart transplant rejection. This CD4 probe is prepared by mixing leukocyte differentiation antigen 4 monoclonal antibody with a solution of 6-hydrazinylnicotinoyl succinimide ester hydrochloride, followed by extraction and reaction to obtain 6-hydrazinylnicotinate-leukocyte differentiation antigen 4 monoclonal antibody; this antibody is then mixed with N-tris (hydroxymethyl) glycine, stannous chloride and technetium for an oscillatory reaction. This CD4 probe exhibits high affinity for CD4 ⁺ T lymphocytes, along with the characteristics of high sensitivity and high specificity, enabling early diagnosis of acute rejection .

HY-135623

Brosuximide	Drug Derivative	Infection Neurological Disease
Brosuximide is a succinimide-type antiepileptic agent .

HY-W414754

2,5-Dioxopyrrolidin-1-yl methyl phthalate	Biochemical Assay Reagents	Others
2,5-Dioxopyrrolidin-1-yl methyl phthalate is a cross-linking agent used for modification of proteins and peptides. 2,5-Dioxopyrrolidin-1-yl methyl phthalate is a reagent for introducing succinimide-activated esters that react with primary amines in proteins and peptides to form stable amide bonds.

Cat. No.	Product Name	Type

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dye
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dye
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

Cat. No.	Product Name	Type

HY-79647

Fmoc-OSu N-(Fmoc-oxy)Succinimide	Biochemical Assay Reagents
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

Fmoc-OSu

N-(Fmoc-oxy)Succinimide

Biochemical Assay Reagents

Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-41877

*Succinimide* pyrrolidine-2,5-dione	Biochemical Assay Reagents
Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent .

HY-75200

N-(Benzyloxycarbonyloxy)succinimide	Biochemical Assay Reagents
N-(Benzyloxycarbonyloxy)succinimide is an efficient amino-protecting reagent in organic synthesis, playing an important role in the field of organic synthesis. N-(Benzyloxycarbonyloxy)succinimide is also a neutral ionophore, which significantly improves the performance of erbium ion (Er ³⁺) sensors and provides a practical tool for the rapid detection of erbium ions in the environment and water quality .

N-(Benzyloxycarbonyloxy)succinimide

Biochemical Assay Reagents

N-(Benzyloxycarbonyloxy)succinimide is an efficient amino-protecting reagent in organic synthesis, playing an important role in the field of organic synthesis. N-(Benzyloxycarbonyloxy)succinimide is also a neutral ionophore, which significantly improves the performance of erbium ion (Er ³⁺) sensors and provides a practical tool for the rapid detection of erbium ions in the environment and water quality .

HY-W414754

2,5-Dioxopyrrolidin-1-yl methyl phthalate	Biochemical Assay Reagents
2,5-Dioxopyrrolidin-1-yl methyl phthalate is a cross-linking agent used for modification of proteins and peptides. 2,5-Dioxopyrrolidin-1-yl methyl phthalate is a reagent for introducing succinimide-activated esters that react with primary amines in proteins and peptides to form stable amide bonds.

Succinimide-AFK-AMC acetate	Bacterial	Infection
Succinimide-AFK-AMC acetate is a marker for P. aeruginosa protease activity using cultured reference strains .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-41877

*Succinimide* pyrrolidine-2,5-dione	Source Classification	Biochemical Assay Reagents
Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent .

Cat. No.	Product Name	Chemical Structure

HY-41877S

Succinimide-15N
Succinimide- ¹⁵N is the ¹⁵N labeled Succinimide. Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent .

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Succinimide

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products