N-(Benzyloxycarbonyloxy)succinimide
Based on 1 Customer Validation
N-(Benzyloxycarbonyloxy)succinimide is an efficient amino-protecting reagent in organic synthesis, playing an important role in the field of organic synthesis. N-(Benzyloxycarbonyloxy)succinimide is also a neutral ionophore, which significantly improves the performance of erbium ion (Er3+) sensors and provides a practical tool for the rapid detection of erbium ions in the environment and water quality.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 13139-17-8
- Formula: C12H11NO5
- Molecular Weight:249.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
N-(Benzyloxycarbonyloxy)succinimide enables selective recognition and potentiometric response to Er3+ ions via neutral ion carrier activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13139-17-8
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Appearance Solid
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Molecular Weight 249.22
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Formula C12H11NO5
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Color White to off-white
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SMILES
O=C(OCC1=CC=CC=C1)ON2C(CCC2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (401.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (10.03 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0125 mL | 20.0626 mL | 40.1252 mL | 100.3130 mL |
| 5 mM | 0.8025 mL | 4.0125 mL | 8.0250 mL | 20.0626 mL | |
| 10 mM | 0.4013 mL | 2.0063 mL | 4.0125 mL | 10.0313 mL | |
| 15 mM | 0.2675 mL | 1.3375 mL | 2.6750 mL | 6.6875 mL | |
| 20 mM | 0.2006 mL | 1.0031 mL | 2.0063 mL | 5.0156 mL | |
| 25 mM | 0.1605 mL | 0.8025 mL | 1.6050 mL | 4.0125 mL | |
| 30 mM | 0.1338 mL | 0.6688 mL | 1.3375 mL | 3.3438 mL | |
| 40 mM | 0.1003 mL | 0.5016 mL | 1.0031 mL | 2.5078 mL | |
| 50 mM | 0.0803 mL | 0.4013 mL | 0.8025 mL | 2.0063 mL | |
| 60 mM | 0.0669 mL | 0.3344 mL | 0.6688 mL | 1.6719 mL | |
| 80 mM | 0.0502 mL | 0.2508 mL | 0.5016 mL | 1.2539 mL | |
| 100 mM | 0.0401 mL | 0.2006 mL | 0.4013 mL | 1.0031 mL |
N-(Benzyloxycarbonyloxy)succinimide Related Classifications
HY-75200 Related Classifications
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