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Cat. No.: HY-B1376R

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Methsuximide (Standard)

Name: Methsuximide (Standard)
Brand: MedChemExpress
SKU: HY-B1376R
Availability: PreOrder

(Synonyms: Mesuximide (Standard); Celontin (Standard))

Methsuximide (Standard) (Mesuximide (Standard); Celontin (Standard)) is the analytical standard of Methsuximide (HY-B1376). This product is intended for research and analytical applications. Methsuximide (Mesuximide) is an orally active succinimide-derived antiepileptic agent. Methsuximide interacts with cytochrome P-450, increases the level of hepatic microsomal cytochrome P-450, and inhibits or competes with the cytochrome P-450 CYP 2C9/10 subtype. Methsuximide can be used in epilepsy-related research.

For research use only. We do not sell to patients.

CAS No.: 77-41-8
Formula: C₁₂H₁₃NO₂
Molecular Weight:203.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Methsuximide (Standard) Chemical Structure

CAS No.: 77-41-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-B1376
Methsuximide

Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 77-41-8
Molecular Weight 203.24
Formula C₁₂H₁₃NO₂
SMILES

O=C(C(C1=CC=CC=C1)(C)C2)N(C)C2=O
Synonyms

Mesuximide (Standard); Celontin (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Orton TC, et al. Effect in rats of subacute administration of ethosuximide, methsuximide and phensuximide on hepatic microsomal enzymes and porphyrin turnover. Biochem Pharmacol. 1972 Aug 15;21(16):2253-61. [Content Brief]

[2]. CHEN G, et al. Anticonvulsant activity and toxicity of phensuximide, methsuximide and ethosuximide. Epilepsia. 1963 Mar;4:66-76.

[3]. Sigler M, et al. Effective and safe but forgotten: methsuximide in intractable epilepsies in childhood. Seizure. 2001 Mar;10(2):120-4. [Content Brief]

[4]. Besag FM, et al. Methsuximide lowers lamotrigine blood levels: A pharmacokinetic antiepileptic drug interaction. Epilepsia. 2000 May;41(5):624-7. [Content Brief]

[5]. Dobrinska MR, et al. Pharmacokinetics of methsuximide and a major metabolite in dogs. Journal of pharmaceutical sciences. 1977 May;66(5):688-92. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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