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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Telomerase activator
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Telomerase activator" in MCE Product Catalog:
9
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Target:
製品番号: HY-P1149
CAS 番号: 307297-39-8
別名: Epithalon; Epithalamin
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製品番号: HY-P1149A
別名: Epithalon TFA; Epithalamin TFA
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製品番号: HY-402361
CAS 番号: 666699-46-3
TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). TERT activator-1 promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. TERT activator-1 promotes adult neurogenesis and enhances neuromuscular function. TERT activator-1 reduces cellular senescence and systemic inflammation in aged mice, and can be used in the study of aging .
製品番号: HY-N2006
CAS 番号: 81907-61-1
Category:
Infection Triterpenes Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields
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製品番号: HY-W021291
CAS 番号: 592-82-5
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製品番号: HY-N1485R
CAS 番号: 78574-94-4
別名: Astramembrangenin (Standard); Cyclosieversigenin (Standard)
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製品番号: HY-169518
CAS 番号: 332939-29-4
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TERT activator-2 (Compound 1030) is a telomerase reverse transcriptase (TERT) activator that can increase the expression of TERT in cells. TERT activator-2 can be used in telomere-related cell lifespan research .
製品番号: HY-N2006R
CAS 番号: 81907-61-1
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製品番号: HY-162688
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研究分野:
Anticancer agent 239 (Compound 5) is a ligand of hTERT promoter G-quadruplex DNA structures (hTERT G4) (Kd = 1.1 μM), and downregulates hTERT expression. Anticancer agent 239 decreases telomerase activity, shortens telomere length, and induces DNA damage, acute cellular senescence, and apoptosis. Anticancer agent 239 causes mitochondrial dysfunction, disrupts iron metabolism and activates ferroptosis in cancer cells. Anticancer agent 239 inhibits tumor growth in MDA-MB-231 xenograft mouse model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
