1 Result for "

TrxR-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TrxR-IN-8" in MCE Product Catalog:

Cat. No.: HY-173403
CAS No.: 2857180-28-8
Research Areas:  

Cancer

TrxR-IN-8 (Compound 6f) is a selective TrxR inhibitor (IC50: 10.2 μM). TrxR-IN-8 induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species (ROS), reducing intracellular thiols, and lowering the glutathione/glutathione ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer (NSCLC) cells .
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