TrxR-IN-8
TrxR-IN-8 (Compound 6f) is a selective TrxR inhibitor (IC50: 10.2 μM). TrxR-IN-8 induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species (ROS), reducing intracellular thiols, and lowering the glutathione/glutathione ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer (NSCLC) cells.
For research use only. We do not sell to patients.
- CAS No.: 2857180-28-8
- Formula: C16H16INO2
- Molecular Weight:381.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2857180-28-8
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Molecular Weight 381.21
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Formula C16H16INO2
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SMILES
COC1=CC(OC)=CC2=C1C3=C(C=[N+]2C)C=CC=C3.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)