2857180-28-8

TrxR-IN-8 Chemical Structure
2857180-28-8

Chemical Structure

TrxR-IN-8

  • CAS No.: 2857180-28-8
  • Formula:C16H16INO2
  • Molecular Weight:381.21

InChIKey: MATWSAIHYPADGV-UHFFFAOYSA-M

SMILES: COC1=CC(OC)=CC2=C1C3=C(C=[N+]2C)C=CC=C3.[I-]

Biological Activity: TrxR-IN-8 (Compound 6f) is a selective TrxR inhibitor (IC50: 10.2 μM). TrxR-IN-8 induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species (ROS), reducing intracellular thiols, and lowering the glutathione/glutathione ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer (NSCLC) cells[1].

Cat. No. Product Name Purity Description Pricing
HY-173403 		TrxR-IN-8 TrxR-IN-8 (Compound 6f) is a selective TrxR inhibitor (IC50: 10.2 μM). TrxR-IN-8 induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species (ROS), reducing intracellular thiols, and lowering the glutathione/glutathione ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer (NSCLC) cells.
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This product is a controlled substance and not for sale in your territory.
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