Unsaturated Fatty Acid

By Targets:	5 alpha Reductase (1) Biochemical Assay Reagents (2) Endogenous Metabolite (3) Isotope-Labeled Compounds (2) Liposome (2) Lipoxygenase (1) Prostaglandin Receptor (1)
By Research Areas:	Cancer (5) Endocrinology (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (11)

Targets Recommended: Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH ELOVL Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13212

(Z)-2-Decenoic acid cis-2-Decenoic Acid	Others	Cancer
(Z)-2-decenoic acid (cis-2-Decenoic acid) is an unsaturated fatty acid produced by Pseudomonas aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. (Z)-2-decenoic acid inhibits biofilm development .

HY-120996B

10(Z)-Pentadecenoic acid cis-10-Pentadecenoic Acid	Biochemical Assay Reagents	Others
10(Z)-Pentadecenoic acid is an unsaturated fatty acid. Unsaturated fatty acids are an important class of lipid molecules whose chemical structure contains one or more double bonds.

HY-118146

Cicrotoic acid

Others Metabolic Disease

Cicrotoic acid is an unsaturated fatty acid that increases bile flow and changes lipid composition .

Cicrotoic acid	Others	Metabolic Disease
Cicrotoic acid is an unsaturated fatty acid that increases bile flow and changes lipid composition .

HY-145952

(2E,9Z)-Octadeca-2,9-dienoic acid	Others	Metabolic Disease
(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, can be used for the research of lipoxygenase-dependent metabolism .

HY-116776

Hexadecatetraenoic acid

Others Metabolic Disease

Hexadecatetraenoic acid is an unsaturated fatty acid that can be isolated from sardine oil .

Hexadecatetraenoic acid	Others	Metabolic Disease
Hexadecatetraenoic acid is an unsaturated fatty acid that can be isolated from sardine oil .

HY-108398A

Mead acid 5,8,11-Eicosatrienoic Acid	Others	Metabolic Disease Cancer
Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency .

HY-121995

(14Z)-14-Eicosenoic acid

Others Others

(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges .

(14Z)-14-Eicosenoic acid	Others	Others
(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges .

HY-101722

Melinamide AC 223; DL-N-(α-Methylbenzyl)linoleamide	Others	Metabolic Disease
Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC₅₀ of 20.9 μM.

HY-134428

Arachidonoyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-113873

10-Thiastearic acid

Others Metabolic Disease

10-Thiastearic acid inhibits desaturation of? stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .
HY-131306

Δ2-cis-Hexadecenoic acid

Others Others

Δ2-cis-Hexadecenoic acid is an unsaturated fatty acid that is a hydrolysate of lipopolysaccharide (HY-D1056) .

10-Thiastearic acid	Others	Metabolic Disease
10-Thiastearic acid inhibits desaturation of? stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .

Δ2-cis-Hexadecenoic acid	Others	Others
Δ2-cis-Hexadecenoic acid is an unsaturated fatty acid that is a hydrolysate of lipopolysaccharide (HY-D1056) .

HY-108398AS

Mead acid-d6 5,8,11-Eicosatrienoic Acid-d₆	Isotope-Labeled Compounds	Metabolic Disease Cancer
Mead acid-d₆ is the deuterium labeled Mead acid. Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency[1].

HY-N12199

All-cis-3,6,9,12,15-octadecapentaenoic acid	Others	Others
All-cis-3,6,9,12,15-octadecapentaenoic acid is an unsaturated fatty acid and can be isolated from the alga Gymnodinium kowalevskii .

HY-133949

8,11-Eicosadiynoic acid	5 alpha Reductase	Endocrinology
8,11-Eicosadiynoic acid, an unsaturated fatty acid, is a steroid 5α-reductase inhibitor. 8,11-Eicosadiynoic acid can be used for the research of acne .

HY-W440982

SOPC PC(18:0/18:1); 2-?Oleoyl-?1-?stearoyl-?sn-?glycero-?3-?phosphocholine	Liposome	Others
SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can be used for various biochemical studies .

HY-153203

Eicosapentaenoyl-CoA triammonium 20:5 Coenzyme A triammonium	Others	Others
Eicosapentaenoyl-CoA triammonium (C20:5-CoA) is an unsaturated fatty acyl-CoA that can assist in the measurement of enzymatic activity of the TrWSD4 enzyme .

HY-108398B

11(Z),14(Z),17(Z)-Eicosatrienoic acid	Endogenous Metabolite	Metabolic Disease
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .

HY-130656

8(Z)-Eicosenoic acid cis-8-Eicosenoic Acid	Endogenous Metabolite	Metabolic Disease
8(Z)-Eicosenoic acid is a cis-unsaturated free fatty acid with a 20-carbon chain. It potentiates acetylcholine (ACh) receptor channel currents without depression and enhances PCKε phosphorylation of a substrate peptide in Xenopus oocytes. 8(Z)-Eicosenoic acid constitutes 6% of the fatty acid pool in seed oil isolated from B. collina.

HY-N10898

(-)-Dihydroguaiaretic acid	Lipoxygenase	Inflammation/Immunology Cancer
(-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC₅₀ value of 7.49 μM (A549 cells) .

HY-21268

Methyl linolenate 1 Publications Verification Linolenic Acid methyl ester	Others	Metabolic Disease
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-143203

18:0-18:2 PE 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine	Liposome	Others
18:0-18:2 PE is a lipid for agents delivering. 18:0-18:2 PE is mainly composed of unsaturated fatty acids. 18:0-18:2 is considered important precursors of important odorants (IOs) in Eriocheir sinensis .

HY-134511

15(S)-HpEPE	Prostaglandin Receptor	Inflammation/Immunology Cancer
15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2 .

HY-21268S

Methyl linolenate-13C18	Isotope-Labeled Compounds	Others
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic Acid; Osbond Acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-134019

Arachidonoyl p-nitroaniline	Others	Others
Arachidonoyl p-nitroaniline is a substrate for the hydrolysis of p-nitroaniline by FAAH in Dictyostelium discoideum with long-chain unsaturated fatty acids. Arachidonoyl p-nitroaniline can be used in enzyme kinetic studies. Examples include determining the hydrolysis rate of Arachidonoyl p-nitroaniline and analyzing the fatty acid amide hydrolase activity of recombinant His-FAAH purified from Dictyostelium to characterize the binding and catalytic specificity of mammalian FAAH enzymes .

HY-N7860

Δ2-cis Eicosenoic acid	Others	Infection
Δ2-cis Eicosenoic acid is an α,β-unsaturated fatty acid that has been extracted from fresh water clams and purified. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats. Δ2-cis Eicosenoic acid and its salts have potential medicinal use for treating diabetes and improving lipid metabolism.

Cat. No.	Product Name

HY-L182

Fatty Acids Compound Library	296 compounds
Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases. MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Fatty Acids Compound Library

296 compounds

Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases.

MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Cat. No.	Product Name	Type

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic Acid; Osbond Acid	Biochemical Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

all-cis-4,7,10,13,16-Docosapentaenoic acid

all-cis-4,7,10,13,16-Docosapentaenoic Acid; Osbond Acid

Biochemical Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-134428

Arachidonoyl coenzyme A lithium	Biochemical Assay Reagents
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-143203

18:0-18:2 PE 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine	Drug Delivery
18:0-18:2 PE is a lipid for agents delivering. 18:0-18:2 PE is mainly composed of unsaturated fatty acids. 18:0-18:2 is considered important precursors of important odorants (IOs) in Eriocheir sinensis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13212

(Z)-2-Decenoic acid cis-2-Decenoic Acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Others
(Z)-2-decenoic acid (cis-2-Decenoic acid) is an unsaturated fatty acid produced by Pseudomonas aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. (Z)-2-decenoic acid inhibits biofilm development .

HY-108398A

Mead acid 5,8,11-Eicosatrienoic Acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Others
Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency .

HY-116776

Hexadecatetraenoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Hexadecatetraenoic acid is an unsaturated fatty acid that can be isolated from sardine oil .

HY-121995

(14Z)-14-Eicosenoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges .

HY-134428

Arachidonoyl coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-N12199

All-cis-3,6,9,12,15-octadecapentaenoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
All-cis-3,6,9,12,15-octadecapentaenoic acid is an unsaturated fatty acid and can be isolated from the alga Gymnodinium kowalevskii .

HY-108398B

11(Z),14(Z),17(Z)-Eicosatrienoic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .

HY-N10898

(-)-Dihydroguaiaretic acid	Structural Classification Source classification Eupomatia laurina R.Br. Phenols Polyphenols Plants Eupomatiaceae	Lipoxygenase
(-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC₅₀ value of 7.49 μM (A549 cells) .

HY-21268

Methyl linolenate 1 Publications Verification Linolenic Acid methyl ester	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-N7860

Δ2-cis Eicosenoic acid	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Others
Δ2-cis Eicosenoic acid is an α,β-unsaturated fatty acid that has been extracted from fresh water clams and purified. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats. Δ2-cis Eicosenoic acid and its salts have potential medicinal use for treating diabetes and improving lipid metabolism.

Cat. No.	Product Name	Chemical Structure

HY-108398AS

Mead acid-d6
Mead acid-d₆ is the deuterium labeled Mead acid. Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency[1].

HY-21268S

Methyl linolenate-13C18
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].

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Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Unsaturated Fatty Acid

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products