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  4. Intralipid 20%

Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response.

For research use only. We do not sell to patients.

CAS No. : 68890-65-3

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Customer Review

Based on 4 publication(s) in Google Scholar

Intralipid 20% Related Antibodies

Top Publications Citing Use of Products

    Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943.  [Abstract]

    Heatmaps of mouse location throughout the free-feeding tests, the consumption of three liquids (i.e., Sucrose, Water, and an Intralipid solution (1.5%)) and time spent in the corresponding zones in the CON and NCI mice.

    Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943.  [Abstract]

    The percentage of time spent in each food zone and percentage of each type of liquid intake.

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    Description

    Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response[1][2].

    In Vitro

    Intralipid 20% (0-0.2 mg/mL) specifically protects immune cells from paclitaxel, but has no effect on tumor cells[1].
    Intralipid 20% (0-0.2 mg/mL, 3 days) promotes polarisation of M0, M1 and M2 macrophages to an M1-like phenotype[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Intralipid 20% Related Antibodies
    In Vivo

    Intralipid (2 g/kg) does not affect phagocytosis and may promote macrophage polarization to the M1 phenotype, as observed in breast cancer tumor sections from Balb/c mice[1].
    Intralipid pretreatment promotes the accumulation of paclitaxel in tumour tissue and induces higher levels of apoptosis in tumour cells. Increased distribution of paclitaxel in mouse RES organs and enhanced inhibition of tumour growth[1].
    Intralipid (5 mL/kg) is more effective than cyclosporin-A in protecting the heart from I/R injury in SD rats, reducing the size of myocardial infarction by approximately 40%[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Clinical Trial
    CAS No.
    Appearance

    Liquid (Density: 0.99 g/cm3)

    Color

    White to off-white

    SMILES

    [Intralipid 20%]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at 4°C, do not freeze
    Purity & Documentation

    SDS (251 KB)

    COA (231 KB)

    Handling Instructions (2659 KB)
    References
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    Intralipid 20% Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Intralipid 20%68890-65-3Biochemical Assay Reagentsfat emulsionnutritional supplementmitochondrial permeabilityinnate immune responseInhibitorinhibitorinhibit

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