alpha-2-macroglobulin

By Targets:	Bacterial (1) Fluorescent Dye (1) Fungal (1) Glutaminase (1) PAI-1 (1) Proteolytic Enzyme (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-165426

HB-230	Fluorescent Dye Glutaminase
HB-230 is a red fluorescent transglutaminase 2 (TG2) probe. HB-230 complexes with TG2 and α2-macroglobulin via the LRP1 pathway for efficient endocytosis. The excitation and emission wavelengths of HB-230 are 649 and 665 nm, respectively .

HY-N18088

2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol	PAI-1	Cardiovascular Disease
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol (Compound 4) is a bispolyphenol. 2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol can be isolated from the brown alga Ecklonia kurome OKAMURA. 2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol exhibits inhibitory activities toward both **α2-macroglobulin (α-M) and α-PI, with IC₅₀**s of 1.9 μg/mL and 0.7 μg/mL, respectively .

HY-E71367

Bromelain (USP)	Proteolytic Enzyme Bacterial Fungal	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Bromelain USP is an orally active proteolytic agent. Bromelain USP converts plasminogen to plasmin to support fibrinolysis, cleaves CD44 adhesion molecules from cell surfaces, and diminishes uPAR expression and uPA activity. Bromelain USP can inhibit the activity of a variety of fungi and bacteria. Bromelain USP can be used for the research of angina pectoris, atherosclerotic disease, fungal infections, bacterial infections, chronic inflammatory bowel disease, and cancer ^[2] .

Cat. No.	Product Name

HY-K0254

Blue Agarose 6FF
MCE Blue Agarose 6FF can be used for the purification of biological macromolecules such as albumin, interferons, nucleotide-dependent enzymes (e.g., kinases, dehydrogenases), α2-macroglobulin, and coagulation factors.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N18088

2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol	Structural Classification other families Phenols Polyphenols Ecklonia kurome Plants Source Classification	PAI-1
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol (Compound 4) is a bispolyphenol. 2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol can be isolated from the brown alga Ecklonia kurome OKAMURA. 2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol exhibits inhibitory activities toward both **α2-macroglobulin (α-M) and α-PI, with IC₅₀**s of 1.9 μg/mL and 0.7 μg/mL, respectively .

Species:	Human (8) Mouse (2)
Tag:	His (7) Avi (1) Fc (3)
Source:	HEK293 (9) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72823

	Alpha-2-macroglobulin Protein, Human (sf9, His) alpha-2-macroglobulin; alpha-2-M; A2M; CPAMD5	Human	Sf9 insect cells
	Alpha-2-macroglobulin Protein, a protease inhibitor and cytokine transporter, belongs to the MEROPS proteinase inhibitor family I39, clan IL. A2M acts on all classes of endoproteases and could potentially be used to slow or halt PTOA by neutralizing catabolic cascades in affected cartilage. A2M can enter into cells and bind to numerous cytokines. It inhibits inflammatory mediators of chondrocytes by blocking IL-1尾/NF-魏B pathway. Alpha-2-macroglobulin Protein, Human (sf9, His) is the recombinant human-derived Alpha-2-macroglobulin protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P76479A

	LRPAP1 Protein, Mouse (HEK293, His) 2 Publications Verification alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; RAP; A2MRAP	Mouse	HEK293
	Low density lipoprotein receptor-related protein associated protein 1 interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands.LRPAP1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LRPAP1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76479

	LRPAP1 Protein, Mouse (HEK293, His, Solution) 2 Publications Verification alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; RAP; A2MRAP	Mouse	HEK293
	Low density lipoprotein receptor-related protein associated protein 1 interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands.LRPAP1 Protein, Mouse (HEK293, His, Solution) is the recombinant mouse-derived LRPAP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76478A

	LRPAP1 Protein, Human (HEK293, C-His) 1 Publications Verification alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; RAP; A2MRAP	Human	HEK293
	The LRPAP1 protein serves as a molecular chaperone for LDL receptor-related proteins and regulates ligand binding throughout the secretory pathway. It transiently interacts with the LRP1/α-2-macroglobulin receptor chain, reducing ligand binding. LRPAP1 Protein, Human (HEK293, C-His) is the recombinant human-derived LRPAP1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76478

	LRPAP1 Protein, Human (HEK293, His, solution) alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; RAP; A2MRAP	Human	HEK293
	The LRPAP1 protein serves as a molecular chaperone for LDL receptor-related proteins and regulates ligand binding throughout the secretory pathway. It transiently interacts with the LRP1/α-2-macroglobulin receptor chain, reducing ligand binding. LRPAP1 Protein, Human (HEK293, His, solution) is the recombinant human-derived LRPAP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P702520

	LRP-1 Cluster II Protein, Human (HEK293, His) 3 Publications Verification A2MR; alpha-2-macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5	Human	HEK293
	LRP-1 Cluster II protein is involved in endocytosis and phagocytosis of apoptotic cells. The LRP-1 Cluster II protein also serves as a receptor for Pseudomonas aeruginosa exotoxin A during microbial infection. LRP-1 Cluster II Protein, Human (HEK293, His) is the recombinant human-derived LRP-1 Cluster II protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P704765

	LRP-1 Cluster II Protein, Human (HEK293, Fc) 1 Publications Verification A2MR; alpha-2-macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5	Human	HEK293
	LRP-1 Cluster II protein is involved in endocytosis and phagocytosis of apoptotic cells. The LRP-1 Cluster II protein also serves as a receptor for Pseudomonas aeruginosa exotoxin A during microbial infection. LRP-1 Cluster II Protein, Human (HEK293, Fc) is the recombinant human-derived LRP-1 Cluster II protein, expressed by HEK293, with C-hFc labeled tag.

HY-P704766

	LRP-1 Cluster III Protein, Human (HEK293, Fc) 1 Publications Verification A2MR; alpha-2-macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5	Human	HEK293
	LRP-1 Cluster III protein is involved in endocytosis and phagocytosis of apoptotic cells. The LRP-1 Cluster III protein also serves as a receptor for Pseudomonas aeruginosa exotoxin A during microbial infection. LRP-1 Cluster III Protein, Human (HEK293, Fc) is the recombinant human-derived LRP-1 Cluster III protein, expressed by HEK293, with C-hFc labeled tag.

HY-P704767

	LRP-1 Cluster IV Protein, Human (HEK293, Fc) 1 Publications Verification A2MR; alpha-2-macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5	Human	HEK293
	LRP-1 Cluster Ⅳ protein is involved in endocytosis and phagocytosis of apoptotic cells. The LRP-1 Cluster Ⅳ protein also serves as a receptor for Pseudomonas aeruginosa exotoxin A during microbial infection. LRP-1 Cluster Ⅳ Protein, Human (HEK293, Fc) is the recombinant human-derived LRP-1 Cluster Ⅳ protein, expressed by HEK293, with C-hFc labeled tag.

HY-P703946

	CD109/CPAMD7 Protein, Human (Biotinylated, HEK293, His, Avi) CD109; CPAMD7; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; 150 kDa TGF-beta-1-binding protein; r150; p180; CPAMD7; Platelet-specific Gov antigen	Human	HEK293
	CD109/CPAMD7 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived CD109/CPAMD7 protein, expressed by HEK293, with C-His & C-Avi tag.

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Host:	Rabbit (6)
Reactivity:	Human (6) Rat (3) Mouse (3)
Application:	IHC-P (6) ICC/IF (5) IF-Tissue (1) IP (3) WB (6) FC (1) ELISA (1)
Isotype:	IgG (6)
Conjugation:	Non-conjugated (6) Biotin (1)
Clonality:	Monoclonal (5) Recombinant (4)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83560

	Alpha-2-Macroglobulin Antibody (YA3305) alpha-2-macroglobulin; A2m; alpha 2M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863 7	WB, IHC-P	Human
	Alpha-2-Macroglobulin Antibody (YA3305) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Alpha-2-Macroglobulin.

HY-P87306

	C4 Antibody (YA6989) Acidic C4 antibody; Acidic complement C4 antibody; Basic C4 antibody; Basic complement C4 antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody; C4, Chido form antibody; C4, Rodgers from antibody; C4A anaphylatoxin antibody; C4A antibody	WB, ICC/IF, IF-Tissue, IHC-P	Human
	C4 Antibody (YA6989) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C4.

HY-P86569

	LRP1 Antibody (YA6261) LRP1; A2MR; APR; Prolow-density lipoprotein receptor-related protein 1; LRP-1; alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD antigen CD91	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	LRP1 Antibody (YA6261) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LRP1.

HY-P86840

	Complement C5 Antibody (YA6533) Complement C5 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 Complement C5 beta chain Complement C5 alpha chain C5a anaphylatoxin Complement C5 alpha' chain C5 CPAMD4	WB, ICC/IF, IHC-P, FC	Human
	Complement C5 Antibody (YA6533) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Complement C5.

HY-P80746

	LRP1 Antibody (YA306) A2MR; alpha 2MR; alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	LRP1 Antibody (YA306) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LRP1.

HY-P80746A

	LRP1 Antibody (YA306)(PBS only) A2MR; alpha 2MR; alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	LRP1 Antibody (YA306) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LRP1.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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alpha-2-macroglobulin

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