182 Results for "

amine derivative

" in MedChemExpress (MCE) Product Catalog:
Products (182)

182 Results for "amine derivative" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-10587
CAS No.: 935693-62-2
Purity:  98.44%
Research Areas:  

Cancer

BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
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27
27 Publications Verification
Cat. No.: HY-108239
CAS No.: 1392399-03-9
Research Areas:  

Cancer

BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
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9
9 Cited Publications
Cat. No.: HY-D0799
CAS No.: 191671-46-2
Target:  

Fluorescent Dye

Research Areas:  

Others

Sulfo-NHS-LC-Biotin sodium is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
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2
2 Cited Publications
Cat. No.: HY-Y1092
CAS No.: 538-75-0
N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
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2
2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
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1
1 Cited Publications
Cat. No.: HY-125924
CAS No.: 474922-26-4
Purity:  99.96%
Synonyms: DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) amine ammonium
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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1
1 Cited Publications
Cat. No.: HY-D1041
CAS No.: 1622335-40-3
Synonyms: ICG-OSu
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
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1
1 Cited Publications
Cat. No.: HY-W013081
CAS No.: 132327-80-1
Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc. Fmoc-Gln(Trt)-OH can be used in solid-phase peptide synthesis .
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1
1 Cited Publications
Cat. No.: HY-D1375
CAS No.: 2183440-44-8
Sulfo-Cy5 amine is a Cyanine 5 (Cy5) (HY-D0821) dye derivative with an amine group. Sulfo-Cy5 amine can endow silica nanoparticles with fluorescent properties, be internalized by cancer cells, and exhibit enhanced photostability after being incorporated into silica nanoparticles. Its maximum excitation wavelength is approximately 646 nm, and maximum emission wavelength is approximately 662 nm .
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1
1 Cited Publications
Cat. No.: HY-32813
CAS No.: 104830-06-0
Synonyms: 3-Iodopyridin-2-amine
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .
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1
1 Cited Publications
Cat. No.: HY-Y0470
CAS No.: 563-41-7
Synonyms: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride
Target:  

VAP-1

Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles .
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1
1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
4-Bromo-7-azaindole is a brominated derivative of 7-azaindole. 4-Bromo-7-azaindole serves as a substrate for palladium-catalyzed C-N and C-O cross-coupling reactions, reacting with amides, amines, amino acid esters and phenols .
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1
1 Cited Publications
Cat. No.: HY-121920
CAS No.: 1539266-20-0
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

25C-NBOH hydrochloride is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine and is a potent agonist of 5-HT receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively) .
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1
1 Cited Publications
Cat. No.: HY-W016288
CAS No.: 7149-49-7
Synonyms: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde
Target:  

Fungal

Research Areas:  

Infection

Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
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Cat. No.: HY-Y1169
CAS No.: 71989-14-5
Synonyms: 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
Research Areas:  

Others

Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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Cat. No.: HY-50097
CAS No.: 55289-36-6
3-Bromo-2-methylaniline is an aromatic amine compound and aniline derivative that serves as a starting material and synthetic precursor. 3-Bromo-2-methylaniline acts as a starting material for the synthesis of 4-bromo-1H-indazole and racemic 3,9-dibromo-4,10-dimethyl-6H,12H-5,11-methanodibenzodiazocine. It also serves as a precursor for the regioselective bromination and subsequent deamination to synthesize 1,2-dibromo-3-methylbenzene .
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Cat. No.: HY-D1336
CAS No.: 2183440-42-6
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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Cat. No.: HY-D0099
CAS No.: 76863-28-0
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
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Cat. No.: HY-141261A
CAS No.: 2245150-18-7
Research Areas:  

Others

Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine hydrochloride is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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Cat. No.: HY-W1048843A
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG5000-amine
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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