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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
arachidonate
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "arachidonate" in MCE Product Catalog:
735
735 Publications Verification
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
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6 Cited Publications
Synonyms: Arachidonyl trifluoromethyl ketone
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AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease .
1
1 Cited Publications
Cat. No.: HY-P72076
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ALOX12; Platelet 12-LOX; arachidonate 12-Lipoxygenase, 12S Type; LOG12; 12S-LOX; arachidonate 15-Lipoxygenase,15S-Type; Polyunsaturated Fatty Acid Lipoxygenase ALOX12; Platelet-Type 12-Lipoxygenase; arachidonate 12-Lipoxygenase, 12S-Type; arachidonate 12-Lipoxygenase; arachidonate (12S)-Lipoxygenase; Linoleate (13S)-Lipoxygenase; arachidonate (15S)-Lipoxygenase; Linoleate 13S-Lipoxygenase; Platelet-Type Lipoxygenase 12; 12-LOX; Lipoxin Synthase 12-LO; 12LO; 12S-Lipoxygenase
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Synonyms: 7-HCA; Umbelliferyl arachidonate; 7-HC-arachidonate
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7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer .
Synonyms: (S)-BEL; (S,E)-Bromoenol lactone
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(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase A2β (iPLA2β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC50 of 2 µM .
Cat. No.: HY-B0215S
CAS No.: 131685-11-5
Synonyms: N-Acetylcysteine-d3; N-Acetyl-L-cysteine-d3; NAC-d3
Cat. No.: HY-W011297
CAS No.: 2566-89-4
Synonyms: Arachidonic acid methyl ester
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Research Areas:
Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy .
Synonyms: ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%
Cat. No.: HY-W011297S1
CAS No.: 19245-55-7
Synonyms: Arachidonic acid methyl ester-d8
Cat. No.: HY-118149
CAS No.: 29774-12-7
Synonyms: 9-D-Hydroperoxylinoleic acid
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Synonyms: N-Acetylcysteine (Standard); N-Acetyl-L-cysteine (Standard); NAC (Standard)
Cat. No.: HY-W013214
CAS No.: 1808-26-0
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12(R)-HETE is a CYP-dependent arachidonic acid metabolite that acts as a proinflammatory lipid mediator. 12 (R)-HETE widely exists in various tissues including the eye, skin and liver. In the cornea, 12(R)-HETE is metabolized via pathways such as β-oxidation into the precursor of 12(R)-HETrE. Without direct receptor binding, 12(R)-HETE indirectly activates AHR-mediated target gene transcription, while inhibiting the enzymatic activity of Na+,K+-ATPase and the intracellular calcium elevation induced by TP agonists. 12(R)-HETE also possesses multiple physiological effects such as chemotaxis, proangiogenesis, vasodilation, natriuresis, diuresis and intraocular pressure reduction, and can be widely used in studies related to psoriasis, inflammatory skin diseases and ocular inflammation .
Cat. No.: HY-165751
CAS No.: 2692623-72-4
Synonyms: (9Z)-9-Octadecen-1-yl(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoate
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Oleyl arachidonate ((9Z)-9-Octadecen-1-yl(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoate) is an ester product.
Cat. No.: HY-113369S
Cat. No.: HY-W013214S
Cat. No.: HY-B0215S1
Synonyms: N-Acetylcysteine-15N; N-Acetyl-L-cysteine-15N; NAC-15N
Cat. No.: HY-165868
CAS No.: 171262-16-1
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Palmityl arachidonate is an ester product.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
