2566-89-4
Chemical Structure
Methyl arachidonate
Synonym(s): Arachidonic acid methyl ester
- CAS No.: 2566-89-4
- Formula:C21H34O2
- Molecular Weight:318.49
IUPAC Name: methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
InChIKey: OFIDNKMQBYGNIW-ZKWNWVNESA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC)=O
Biological Activity: Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methyl arachidonate | 99.9% | Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy. | ||||||||||||||||||||
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Methyl arachidonate-d5 | Methyl arachidonate-d5 is the deuterium labeled Arachidonic acid methyl ester. | |||||||||||||||||||||
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Methyl arachidonate-d8 | 99.9% | Methyl arachidonate-d8 is the deuterium labeled Arachidonic acid methyl ester. | ||||||||||||||||||||
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Methyl arachidonate-13C5 | Methyl arachidonate-13C5 (Arachidonic acid methyl ester-13C5) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite. | |||||||||||||||||||||
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Methyl arachidonate-13C4 | Methyl arachidonate-13C4 (Arachidonic acid methyl ester-13C4) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite. | |||||||||||||||||||||
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- [1]. Fan XT, et al. Arachidonic acid and related methyl ester mediate protein kinase C activation in intact platelets through the arachidonate metabolism pathways. Biochem Biophys Res Commun. 1990;169(3):933-940. [Content Brief]
- [2]. Hume EM, et al. Fat-deficiency disease of rats. The relative curative potencies of methyl linoleate and methyl arachidonate with a note on the action of the methyl esters of fatty acids from cod liver oil. Biochem J. 1940 Jun;34(6):879-83. [Content Brief]
