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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
arginine 3
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "arginine 3" in MCE Product Catalog:
GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4 .
Cat. No.: HY-182275
Target:
Research Areas:
PROTAC PRMT1 degrader-1 (compound 4) is a PRMT1 PROTAC degrader, with a DC50 of 0.77 μM (MCF-7 cells). PROTAC PRMT1 degrader-1 recruits the CRBN E3 ubiquitin ligase to induce proteasome-dependent degradation of PRMT1; it also forms a ternary complex with PRMT1 and CRBN, promoting ubiquitination and subsequent proteasomal degradation of PRMT1. PROTAC PRMT1 degrader-1 reduces the level of asymmetric dimethylarginine in cancer cells, as well as the level of asymmetric dimethylation of arginine 3 on histone H4, while inhibiting the growth of various cancer cells. PROTAC PRMT1 degrader-1 can be used in the research of breast cancer and melanoma .
Cat. No.: HY-P701623
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM8; Lysine (K)-Specific Demethylase 8; Prev. JMJD5; JmjC Arginyl-Hydroxylase; Bifunctional Peptidase And Arginyl-Hydroxylase JMJD5; FLJ13798; Jumonji C Domain-Containing Protein 5; Jumonji Domain-Containing Protein 5; L-arginine (3R)-Hydroxylase KDM8; L
Species:
Human
Source:
E. coli
Cat. No.: HY-P701624
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM8; Lysine (K)-Specific Demethylase 8; Prev. JMJD5; JmjC Arginyl-Hydroxylase; Bifunctional Peptidase And Arginyl-Hydroxylase JMJD5; FLJ13798; Jumonji C Domain-Containing Protein 5; Jumonji Domain-Containing Protein 5; L-arginine (3R)-Hydroxylase KDM8; L
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
