871085-49-3
Chemical Structure
GPR35 agonist 4
- CAS No.: 871085-49-3
- Formula:C12H9NO5S
- Molecular Weight:279.27
IUPAC Name: (Z)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
InChIKey: WXMCOLGPDOYHNK-UITAMQMPSA-N
SMILES: O=C(NC(S/1)=O)C1=C\C2=CC=C(C=C2)OCC(O)=O.[(Z)]
Biological Activity: GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
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GPR35 agonist 4 | 99.32% | GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4. | ||||||||||||||||||||
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Keywords