77 Results for "

benzamide

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "benzamide" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-Z0283
CAS No.: 55-21-0
Synonyms: Benzenecarboxamide; Phenylamide
Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature .
loading...
    loading...
12
12 Publications Verification
Cat. No.: HY-B1019
CAS No.: 15676-16-1
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-12505
CAS No.: 215923-54-9
Purity:  99.62%
Target:  

iGluR Autophagy

Research Areas:  

Neurological Disease

CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0068
CAS No.: 123040-16-4
Synonyms: Y-25130 hydrochloride
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1059
CAS No.: 23672-07-3
Synonyms: RV-12309; S-(-)-Sulpiride
Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1103
CAS No.: 1030384-98-5
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
loading...
    loading...
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
loading...
    loading...
Cat. No.: HY-120469
CAS No.: 1258292-64-6
Purity:  99.80%
Target:  

JAK

Research Areas:  

Inflammation/Immunology

GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor with Kis of 4.8, 0.7, 0.7, and 0.4 nM for TYK2, JAK1, JAK2, and JAK3, respectively .
loading...
    loading...
Cat. No.: HY-112731
CAS No.: 1011244-68-0
Purity:  99.98%
Synonyms: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
loading...
    loading...
Cat. No.: HY-147342
CAS No.: 156724-91-3
Target:  

Drug Metabolite IMPDH

Research Areas:  

Cancer

β-Benzamide adenine dinucleotide is a biologically active metabolite of benzamide riboside. β-Benzamide adenine dinucleotide is a competitive inhibitor of human NAD kinase with a Ki value of 90 μM, and inhibits human IMPDH with IC50 values of 0.787 μM and 0.884 μM for type I and type II, respectively. β-Benzamide adenine dinucleotide exhibits inhibitory activities against lactate dehydrogenase, glutamate dehydrogenase, and malate dehydrogenase. β-Benzamide adenine dinucleotide can be used for the study of chronic myelogenous leukemia .
loading...
    loading...
Cat. No.: HY-112547
CAS No.: 1034297-58-9
Synonyms: CRT0066051
Target:  

PKD

Research Areas:  

Others

CRT5, a pyrazine benzamide, is a potent and selective inhibitor for all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively). CRT5 decreases VEGF-induced endothelial migration, proliferation and tubulogenesis .
loading...
    loading...
Cat. No.: HY-B1019R
CAS No.: 15676-16-1
Sulpiride (Standard) is the analytical standard of Sulpiride. This product is intended for research and analytical applications. Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer .
loading...
    loading...
Cat. No.: HY-W000887
CAS No.: 180516-87-4
4-Carboxyphenylboronic acid pinacol ester can be used as a starting material for N-(2-acryloylamino-ethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (AEBB). 4-Carboxyphenylboronic acid pinacol ester can be used to crosslink epoxidized natural rubber (ENR) to silica. 4-Carboxyphenylboronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
loading...
    loading...
Cat. No.: HY-Z0283S
CAS No.: 31656-62-9
Synonyms: Benzenecarboxamide-15N; Phenylamide-15N
Benzamide- 15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP) .
loading...
    loading...
Cat. No.: HY-46832
CAS No.: 1214-48-8
Target:  

Drug Intermediate

Research Areas:  

Others

2-Amino-N-(pyridin-3-ylmethyl)benzamide is a drug intermediate for synthesis of various active compounds.
loading...
    loading...
Cat. No.: HY-W055845
CAS No.: 19227-13-5
Research Areas:  

Others

4-Methylbenzamide oxime is a model of benzamide oxime and can be used as a substrate for mitochondrial amidoxime reducing component (mARC) catalytic enzyme reduction .
loading...
    loading...
Cat. No.: HY-14147
CAS No.: 112727-80-7
Purity:  98.36%
Synonyms: BRL 24924
Target:  

5-HT Receptor

Research Areas:  

Metabolic Disease

Renzapride (BRL 24924), a substituted benzamide, is a full 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride (BRL 24924) is also a 5HT2b and 5HT3 receptor antagonist . Renzapride could be used for constipation predominant irritable bowel syndrome (C-IBS) study .
loading...
    loading...
Cat. No.: HY-W711852
CAS No.: 1235489-47-0
Synonyms: Benzenecarboxamide-d5; Phenylamide-d5
Benzamide-d5 (Benzenecarboxamide-d5) is deuterium labeled Benzamide. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature .
loading...
    loading...
Cat. No.: HY-403978S
CAS No.: 1447799-45-2
Benzamide-C6-N-Boc-C2-amide-phenol-d5 is the deuterium labeled Benzamide-C6-N-Boc-C2-amide-phenol.
loading...
    loading...
Cat. No.: HY-145488
CAS No.: 2222445-87-4
Purity:  98.92%
Target:  

ADC Linkers

Research Areas:  

Cancer

MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
loading...
    loading...