215923-54-9
215923-54-9
Chemical Structure
CX546
- CAS No.: 215923-54-9
- Formula:C14H17NO3
- Molecular Weight:247.29
IUPAC Name: (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(piperidin-1-yl)methanone
InChIKey: LJUNPHMOGNFFOS-UHFFFAOYSA-N
SMILES: O=C(N1CCCCC1)C2=CC=C(OCCO3)C3=C2
Biological Activity: CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects[1][2].
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CX546 | 99.47% | CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects. | ||||||||||||||||||||
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References
- [1]. Lauterborn JC, et al. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci. 2000 Jan 1;20(1):8-21. [Content Brief]
- [2]. Lipina T, et al. The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice. Neuropsychopharmacology. 2007 Apr;32(4):745-56. [Content Brief]
