1258292-64-6
1258292-64-6
Chemical Structure
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
- CAS No.: 1258292-64-6
- Formula:C16H13Cl2N3O2
- Molecular Weight:350.20
IUPAC Name: 2,6-dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
InChIKey: IAFNAEGXTKTGHN-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(NC(C2CC2)=O)=NC=C1)C3=C(Cl)C=CC=C3Cl
Biological Activity: GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor with Kis of 4.8, 0.7, 0.7, and 0.4 nM for TYK2, JAK1, JAK2, and JAK3, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide | 99.80% | GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor with Kis of 4.8, 0.7, 0.7, and 0.4 nM for TYK2, JAK1, JAK2, and JAK3, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
