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Raclopride tartrate

11 Cited Publications
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Based on 11 publication(s) in Google Scholar

Raclopride tartrate is a selective dopamine D2/D3 receptor antagonist with potential antipsychotic effects. Raclopride tartrate binds to D2 and D3 receptors with Kis of 1.8 nM and 3.5 nM, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 98185-20-7
  • Formula: C19H26Cl2N2O9
  • Molecular Weight:497.32
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Raclopride tartrate Chemical Structure
    Raclopride tartrate Chemical Structure
  • Experimental Validation Results for Raclopride tartrate
  • Experimental Validation Results for Raclopride tartrate
  • Experimental Validation Results for Raclopride tartrate
  • Experimental Validation Results for Raclopride tartrate
  • Experimental Validation Results for Raclopride tartrate
CAS No.: 98185-20-7
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  • Raclopride tartrate Chemical Structure
    Raclopride tartrate Chemical Structure
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    Raclopride tartrate purchased from MedChemExpress. Usage Cited in: Neuron. 2026 May 19:S0896-6273(26)00332-6. [Abstract]

    Customer Validation
     Raclopride (1 μg/0.3 μL; ICV) alone and combined antagonist treatment both increased spindle density, with minimal effects on other spindle parameters in C57BL/6J mice.

  • 1/16

    Raclopride tartrate purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2026 Jan 14. [Abstract]

    Customer Validation
     Graphs of active nose pokes with Raclopride (0.3 mg/kg; s.c.; single dose) [i: Vehicle n = 10, Raclopride n = 11, Fgroup×session(1, 19) = 23.944, P < 0.001, two-way RM ANOVA test] treatment in cocaine-primed reinstatement test. The results showed that during the reinstatement test, active nose pokes were inhibited by Raclopride.

  • 1/16

    Raclopride tartrate purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2026 Jan 14. [Abstract]

    Customer Validation
     Raclopride (a D2R full antagonist, 0.3 mg/kg; s.c.; single dose; C57BL/6 J mice) significantly increased cAMP signaling in the NAcC.

  • 1/16

    Raclopride tartrate purchased from MedChemExpress. Usage Cited in: Brain Res Bull. 2025 Aug:228:111409. [Abstract]

    Customer Validation
     D2 receptor antagonist Behavioral (0.2 μg/side, 400 nL; ICV; SNI mice) reversed the alleviation of static and dynamic mechanical allodynia induced by the activation of vPAG-LSD dopaminergic projections and significantly increased the duration of spontaneous paw lifting and licking.

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    Raclopride tartrate purchased from MedChemExpress. Usage Cited in: Cell Rep. 2024 Sep 10;43(9):114717. [Abstract]

    Customer Validation
     Locomotor activity depicted in 5-min segments (left), total distance moved (middle), and speed (right) in the open field over a 60-min period. In the OFT, both SCH-23390 (0.125 mg/kg; i.p.; single dose; HY-19545A) and Raclopride (1 mg/kg; i.p.; single dose) reduced the hyperactivity of VTADA-shHrh2 mice. Additionally, both SCH-23390 and Raclopride decreased locomotor activity in VTADA-GFP mice during the OFT without affecting their travel speed.

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