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Results for "

bioconjugation

" in MedChemExpress (MCE) Product Catalog:

134

Inhibitors & Agonists

7

Fluorescent Dye

96

Biochemical Assay Reagents

24

Click Chemistry

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W441011

    Liposome Neurological Disease Inflammation/Immunology Cancer
    DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
    DSPE-NHS
  • HY-174892

    Biochemical Assay Reagents Others
    Biotin-PEG5-NHS ester is a heterobifunctional crosslinker as well as a polyethylene glycol-containing bioconjugation reagent. Biotin-PEG5-NHS ester is widely used in scientific research fields such as the construction of highly sensitive biosensors, the development of targeted drug delivery systems (e.g., liposome modification), immunofluorescence imaging, and protein affinity purification, and serves as an important tool for achieving precise labeling and functionalization of biomolecules .
    Biotin-PEG5-NHS ester
  • HY-151655

    ADC Linker Others
    11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling . 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    11-Azidoundecanoic acid
  • HY-155881

    mPEG550-NH2

    Biochemical Assay Reagents Cancer
    mPEG550-amine (mPEG550-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG550-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
    mPEG550-amine
  • HY-125372

    ABAO

    Biochemical Assay Reagents Others
    2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n



    2-Amino benzamidoxime
  • HY-160155

    Biochemical Assay Reagents Others
    Cholesteryl-Teg azide is a cholesterol azide and can be used as a ligand for bioconjugation. Cholesteryl-Teg azide can modify RNA strands .
    Cholesteryl-Teg azide
  • HY-W1123936B

    DBCO-PEG1000-Folate

    Folate Receptor (FR) Cancer
    DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .
    DBCO-PEG1000-FA
  • HY-145485

    PROTAC Linkers Others
    HS-PEG3400-SH, a linear homobifunctional PEG, is a cross-linker. HS-PEG-SH can be used for drug delivery and preparation of PEG hydrogels .
    HS-PEG3400-SH
  • HY-W190824

    Biochemical Assay Reagents Others
    Biotin-PEG8-azide is a bioconjugation reagent. Biotin-PEG8-azide consists of biotin, PEG8 linker and azide group and serves as a modifying linker in click reactions. Biotin-PEG8-azide can be used for research related to click chemistry .
    Biotin-PEG8-azide
  • HY-158072

    Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs) Cancer
    DOTAM-NHS-ester is a bifunctional chelator and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester combines the efficient metal chelating ability of DOTAM macrocyclic ligands with the bioconjugation function of NHS ester active groups, and can be widely used in the biomedical field for metal labeling, molecular imaging and drug delivery development .
    DOTAM-NHS-ester
  • HY-W588706

    Biochemical Assay Reagents Others
    Tetrazine-PEG5-SS-NHS ester is a heterobifunctional crosslinking agent, a PEG derivative composed of NHS ester. NHS ester can bind to amino acids or other amino-containing molecules. Tetrazine-PEG5-SS-NHS ester is used in bioconjugation, bioorthogonal chemistry, and delivery.
    Tetrazine-PEG5-SS-NHS ester
  • HY-W190766

    S-Acetyl-dPEG(R)8-NHS ester

    Biochemical Assay Reagents
    dPEG(R)8-SATA (S-Acetyl-dPEG(R)8-NHS ester) is a bioconjugation reagent with excellent biocompatibility and high selectivity. dPEG(R)8-SATA can be used to label and cross-link biomolecules and promote the interaction between biomolecules. dPEG(R)8-SATA plays an important role in bioimaging and compound delivery systems.
    dPEG(R)8-SATA
  • HY-151818

    ADC Linker Others
    12-Azido-dodecanoyl-OSu is a click chemistry reagent containing an azide group. 12-Azido-dodecanoyl-OSu can be used as a hydrophobic bioconjugation linker. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    12-Azido-dodecanoyl-OSu
  • HY-D1406

    Fluorescent Dye Others
    L-Biotin-NH-5MP-Br is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
    L-Biotin-NH-5MP-Br
  • HY-164785

    Drug Intermediate Others
    TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery.
    TCO-PEG5-C2-Mal
  • HY-168939A

    Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000)
  • HY-151752

    ADC Linker Others
    Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry .
    Mal-AMCHC-N-Propargylamide
  • HY-W1123936C

    DBCO-PEG2000-Folate

    Folate Receptor (FR) Others
    DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .
    DBCO-PEG2000-FA
  • HY-W190755

    Biochemical Assay Reagents Others
    Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
    Mal-PEG4-mal
  • HY-151640

    ADC Linker Others
    Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-DAP-N3
  • HY-W714969A

    Phosphoramidites Others
    BCN-CE-phosphoramidite is an oligonucleotide modifier containing a BCN strained cyclooctyne structure. BCN-CE-phosphoramidite possesses bioorthogonal reactivity and bioconjugation capability .
    BCN-CE-phosphoramidite
  • HY-W1123936D

    DBCO-PEG3400-Folate

    Folate Receptor (FR) Others
    DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .
    DBCO-PEG3400-FA
  • HY-111945

    Fluorescent Dye Others
    Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λex=465nm and λem539 nm)[1].
    Cys modifier 1
  • HY-151636

    ADC Linker Others
    10-Undecynoyl-OSu is a click chemistry reagent. 10-Undecynoyl-OSu is used as a hydrophobic bioconjugation linker that can be further modified at the alkyne using Click-chemistry .
    10-Undecynoyl-OSu
  • HY-D1403

    Fluorescent Dye Cancer
    L-Biotin-NH-5MP is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
    L-Biotin-NH-5MP
  • HY-D1404

    Fluorescent Dye Others
    5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation . 5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    5MP-Propargyl
  • HY-D1407

    Fluorescent Dye Others
    Br-5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation . Br-5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Br-5MP-Propargyl
  • HY-168939

    Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000)
  • HY-W1123936H

    DBCO-PEG10000-Folate

    Folate Receptor (FR) Others
    DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .
    DBCO-PEG10000-FA
  • HY-W1123936E

    DBCO-PEG5000-Folate

    Folate Receptor (FR) Others
    DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .
    DBCO-PEG5000-FA
  • HY-W190746

    Biochemical Assay Reagents Others
    Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
    Mal-PEG1-Mal
  • HY-D1402

    Fluorescent Dye Others
    5MP-Fluorescein (compound 3e) is a fluorescein dye base on 5-Methylene pyrrolone (5MP).5-Methylene pyrrolones are highly thiol-specific and tracelessly removable bioconjugation tools .
    5MP-Fluorescein
  • HY-W591965

    Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    t-Boc-aminooxy-pentane-amine
  • HY-172290

    ADC Linker Cancer
    Benzyl N1-[PEG1-NHS] -N6-(t-Boc)-L-lysinate is a multifunctional ADC linker consisting of a terminal benzyl group, one PEG unit, an NHS ester, and a t-Boc-protected L-lysine, often used for bioconjugation and chemical modifications in R&D.
    Benzyl N1-[PEG1-NHS]-N6-(t-Boc)-L-lysinate
  • HY-W440907

    Biochemical Assay Reagents Others
    DSPE-PEG5000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG5000-Vinylsulfone
  • HY-W440905

    Biochemical Assay Reagents Others
    DSPE-PEG2000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG2000-Vinylsulfone
  • HY-W440904

    Biochemical Assay Reagents Others
    DSPE-PEG1000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG1000-Vinylsulfone
  • HY-W800649

    Biochemical Assay Reagents Others
    Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
    Aminooxy-PEG2-amine hydrochloride
  • HY-W354021

    Biochemical Assay Reagents Others
    Bis-N-succinimidyl diglycolic acid is a multifunctional crosslinker. Bis-N-succinimidyl diglycolic acid finds application in bioconjugation and protein labeling .
    Bis-N-succinimidyl diglycolic acid
  • HY-185163

    Biochemical Assay Reagents Others
    Sulfo DBCO-Gly-Gly-Gly is a crosslinker/handle installer with dibenzocyclooctyne (DBCO). Sulfo DBCO-Gly-Gly-Gly can be used in bioconjugation research .
    Sulfo DBCO-Gly-Gly-Gly
  • HY-W800727

    Biochemical Assay Reagents Others
    BB1-acid was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
    BB1-acid
  • HY-174941

    Biochemical Assay Reagents Others
    Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
    Mal-PEG18-acid
  • HY-168939C

    Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000)
  • HY-W800726

    Biochemical Assay Reagents Others
    BB1-NHS ester is amine reactive at pH 7-9 to form a stable, irreversible amide bond. It was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
    BB1-NHS ester
  • HY-168939B

    Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400)
  • HY-W451415

    Biochemical Assay Reagents Others
    NHS-PEG-NHS is a derivative of activated polyethylene glycol (PEG) that can modify functional groups on protein surfaces via covalent binding. NHS-PEG-NHS serves as a bioconjugation modification reagent for modifying proteins, enzymes, peptides and antibodies .
    NHS-PEG-NHS
  • HY-W190925

    Biochemical Assay Reagents Others
    APN-C3-biotin is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and Biotin. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.
    APN-C3-biotin
  • HY-182663A

    Biochemical Assay Reagents Others
    Dextran-NH2 (MW 10 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 10 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
    Dextran-NH2 (MW 10 kDa)
  • HY-182663E

    Biochemical Assay Reagents Others
    Dextran-NH2 (MW 500 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 500 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
    Dextran-NH2 (MW 500 kDa)
  • HY-182663B

    Biochemical Assay Reagents Others
    Dextran-NH2 (MW 70 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 70 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
    Dextran-NH2 (MW 70 kDa)

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