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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
centrosomal
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "centrosomal" in MCE Product Catalog:
JH295 is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 inhibits cellular Nek2 via alkylation of Cys22. JH295 is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint . JH295 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-P11118A
Synonyms: CAPture peptide, biotin-CCDC61 (334-366) TFA
Target:
Research Areas:
Cat. No.: HY-12797
CAS No.: 888042-13-5
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GF 15 is an inhibitor of centrosomal clustering during cell mitosis, with an EC50 value of 900 nM for inducing multipolar spindles. GF 15 is a derivative of griseofulvin that inhibits tubulin polymerization at concentrations above 25 μM. GF 15 inhibits tumor growth and significantly prolongs survival in mouse xenograft models of human colon cancer and multiple myeloma .
JH295 hydrate is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 hydrate inhibits cellular Nek2 via alkylation of Cys22. JH295 hydrate is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint . JH295 (hydrate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-P11118
Synonyms: CAPture peptide, biotin-CCDC61 (334-366)
Target:
Research Areas:
Cat. No.: HY-P76818
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEP57; centrosomal Protein 57kDa; centrosomal Protein 57; FGF2-Interacting Protein; Translokin; Proliferation-Inducing Protein 8; TSP57; Cep57; centrosomal Protein Of 57 KDa; MVA2; KIAA0092; PIG8; Testis-Specific Protein 57
Cat. No.: HY-P703331
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CEP55; centrosomal Protein 55kDa; Prev. C10orf3; URCC6; centrosomal Protein Of 55 KDa; Chromosome 10 Open Reading Frame 3; CT111; MARCH; Up-Regulated In Colon Cancer 6; Cep55; Cancer/Testis Antigen 111; centrosomal Protein 55; FLJ10540
Cat. No.: HY-P703332
Synonyms: CEP55; centrosomal Protein 55kDa; Prev. C10orf3; URCC6; centrosomal Protein Of 55 KDa; Chromosome 10 Open Reading Frame 3; CT111; MARCH; Up-Regulated In Colon Cancer 6; Cep55; Cancer/Testis Antigen 111; centrosomal Protein 55; FLJ10540
Cat. No.: HY-P76927
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CEP43; FGFR1 Oncogene Partner; Prev. FGFR1OP; Fibroblast Growth Factor Receptor 1 Oncogene Partner; centrosomal Protein 43; FOP
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Source:
Cat. No.: HY-165369
CAS No.: 1192754-38-3
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IBPR002 is an inhibitor of Aurora kinase A and Aurora kinase B, with IC50 values of 41 nM and 17 nM, respectively. IBPR002 disrupts the nucleation and bundling of kinetochore microtubules, impairs the bipolarity of mitotic spindles, and promotes the binding of non-phosphorylated hepatoma up-regulated protein (HURP) to microtubules derived from the mother centrosome. IBPR002 reduces tumorigenesis levels in a colorectal cancer xenograft model using athymic nude mice. IBPR002 is applicable for research related to colorectal cancer .
Cat. No.: HY-P82250
Synonyms: B cell antigen receptor Ig beta associated protein 1; BPM 90; BPM L; BPM-L; BPM90; BPML; IBAP 1; Imp 9; Importin 9; Novel centrosomal protein RanBPM; RAN binding protein 9; Ran binding protein centrosomal; Ran Binding Protein in the Microtubule organizing center; Ran binding protein M; Ran BP9; Ran-binding protein 9; Ran-binding protein M; RANB9_HUMAN; RanBP 7; RANBP 9; RanBP7; RanBP9; RanBPM.
Cat. No.: HY-P85542
Synonyms: B cell antigen receptor Ig beta associated protein 1; BPM 90; BPM L; BPM-L; BPM90; BPML; IBAP 1; Imp 9; Importin 9; Novel centrosomal protein RanBPM; RAN binding protein 9; Ran binding protein centrosomal; Ran Binding Protein in the Microtubule organizing center; Ran binding protein M; Ran BP9; Ran-binding protein 9; Ran-binding protein M; RANB9_HUMAN; RanBP 7; RANBP 9; RanBP7; RanBP9; RanBPM.
Cat. No.: HY-P86996
Synonyms: Centrosome Marker antibody; Glycogen synthase kinase 3 beta interacting protein antibody; GSK3B interacting protein antibody; h Glycogen synthase kinase 3 beta-interacting protein antibody; hNinein antibody; KIAA1565 antibody; NIN antibody; NIN protein antibody; NIN_HUMAN antibody; ninein (GSK3B interacting protein) antibody; Centrosome Marker antibody; Glycogen synthase kinase 3 beta interacting protein antibody; GSK3B interacting protein antibody; h Glycogen synthase kinase 3 beta-interacting protein antibody; hNinein antibody; KIAA1565 antibody; NIN antibody; NIN protein antibody; NIN_HUMAN antibody; ninein (GSK3B interacting protein) antibody; Ninein antibody; Ninein centrosomal protein antibody; SCKL7 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
