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Cat. No.: HY-P86279

POC5 Antibody (YA5971)

Name: POC5 Antibody (YA5971)
Brand: MedChemExpress
SKU: HY-P86279
Availability: PreOrder

(Synonyms: POC5; C5orf37; Centrosomal protein POC5 ; Protein of centriole 5; hPOC5; )

POC5 Antibody (YA5971) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POC5.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio	1:1000-5000	1:100-300

Description

POC5 Antibody (YA5971) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POC5.

Host Rabbit
Clonality Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 63 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

POC5 is essential for the assembly of the distal half of centrioles, required for centriole elongation. Acts as a negative regulator of centriole elongation^[1]^[2]^[3].
Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Isoforms & Post-Translational Modification

Q8NA72 has 3 isomers: Q8NA72-1: 63351 Da (predicted); Q8NA72-2: 44255 Da (predicted); Q8NA72-3: 60784 Da (predicted).
Hyperphosphorylated during recruitment to procentrioles in G2/M phase
Subunit

Interacts with CETN2 and CETN3 (PubMed:19349582). Forms a microtubule-associated complex with POC1B, CETN2 and FAM161A (PubMed:32110738). Interacts with CCDC15 (PubMed:37934472)
SwissProt ID

Q8NA72
Gene ID

134359 [NCBI]
Synonyms

POC5; C5orf37; Centrosomal protein POC5 ; Protein of centriole 5; hPOC5;