12 Results for "

chimeric antigen receptor

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "chimeric antigen receptor" in MCE Product Catalog:

Cat. No.: HY-P990534
Synonyms: K1-70

Target:  

TSH Receptor

Research Areas:  

Endocrinology Cancer

Anti-TSHR Antibody (K1-70) is an anti-TSHR monoclonal antibody. Anti-TSHR Antibody (K1-70) incorporates a single-chain variable fragment into a chimeric antigen receptor to redirect T cells to TSHR-expressing cells. Anti-TSHR Antibody (K1-70) shows antitumor activity with no apparent toxicity. Anti-TSHR Antibody (K1-70) can be used for the research of differentiated thyroid cancer (DTC) .
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Cat. No.: HY-P99825
CAS No.: 2171034-70-9

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Relfovetmab is a monoclonal antibody and also serves as a single-chain variable fragment component for engineering chimeric antigen receptors (CAR) in modified CAR-T cells. Relfovetmab can be used in studies of cancer and immune disorders .
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Cat. No.: HY-153085
Target:  

CD19

Research Areas:  

Inflammation/Immunology Cancer

CD19 CAR circRNA will express CD19 car protein, and can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction.
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Cat. No.: HY-P10417
CAS No.: 222557-93-9
Target:  

Integrin IFNAR

Research Areas:  

Cancer

RTDLDSLRTYTL is an Alpha (v) beta (6) integrin (avb6) inhibitor with high affinity and specificity. RTDLDSLRTYTL binds to avb6 integrin, a peptide sequence that activates cytotoxicity and cytokine production in T cells, such as interferon-gamma. RTDLDSLRTYTL is designed through a chimeric T cell antigen receptor (CAR) so that T cells can be redirected to specifically recognize and attack tumor cells. RTDLDSLRTYTL can be used in the research of cancer immunotherapy and targeted drug development .
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Cat. No.: HY-157288
Research Areas:  

Metabolic Disease

(R)-Phe-A110/B319, a hapten, is a selective binder to tumor-associated antigens. (R)-Phe-A110/B319 has a 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex. (R)-Phe-A110/B319 can be used for the research of conditional chimeric antigen receptor T (CAR-T) cell activation and tumor targeting .
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Cat. No.: HY-P10021
CAS No.: 1221082-45-6
Synonyms: hTERT (691–705)
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Tapderimotide (hTERT (691–705)) is an immunological agent for active immunization .
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Cat. No.: HY-188021
Target:  

mRNA CD22

Research Areas:  

Cancer

cis a chimeric antigen receptor mRNA targeting CD22. When delivered via CD8-targeted LNP, CD22 CAR mRNA inhibits tumor growth in Nalm6 tumor-bearing mouse models. CD22 CAR mRNA can be used for research on hematologic malignancies .
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Cat. No.: HY-P992338
CT-1119 is an autologous human anti-Mesothelin chimeric antigen receptor macrophage (CAR-M). CT-1119 mediates CAR-dependent, antigen-dependent functional activities. CT-1119 acts as a phagocytosis inducer, tumor cell killer, pro-inflammatory cytokine inducer, and M1 macrophage polarizer. CT-1119 exhibits stronger resistance to M2 repolarization and reduces tumor burden in a mouse lung cancer xenograft model. CT-1119 can be used for the research of mesothelin-expressing solid tumors .
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Cat. No.: HY-P11129
CAS No.: 289905-22-2
Target:  

Peptides

Research Areas:  

Cancer

MAGE-A4 (286-294) is a polypeptide derived from the 286th to 294th amino acids of the MAGE-A4 protein. MAGE-A4 (286-294) binds HLA-­A*02 with an affinity of 560.08 nM and an IC50 of 8.52 nM. MAGE-A4 (286-294) can be detected in various types of cancers (such as esophageal cancer, lung squamous cell carcinoma, bladder cancer). MAGE-A4 (286-294) can be used to produce CAR-T cells and to develop CAR-T cell therapy .
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Cat. No.: HY-185975
Target:  

mRNA

Research Areas:  

Others

Scarless CD19 CAR circular RNA (CVB3) is a circular RNA that uses CVB3 IRES to mediate scarless expression of the CD19 chimeric antigen receptor (CAR) for CAR-T cell research. This circular RNA features a scarless circularization design, eliminating the need for a linker or adapter sequence between the 5′ and 3′ ends, and achieving efficient circularization and expression without the need for optimized UTR elements.
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Cat. No.: HY-P10417B
Target:  

Integrin IFNAR

Research Areas:  

Cancer

RTDLDSLRTYTL TFA is an Alpha (v) beta (6) integrin (avb6) inhibitor with high affinity and specificity. RTDLDSLRTYTL TFA binds to avb6 integrin, a peptide sequence that activates cytotoxicity and cytokine production in T cells, such as interferon-gamma. RTDLDSLRTYTL TFA is designed through a chimeric T cell antigen receptor (CAR) so that T cells can be redirected to specifically recognize and attack tumor cells. RTDLDSLRTYTL TFA can be used in the research of cancer immunotherapy and targeted drug development .
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Cat. No.: HY-185260
Target:  

Liposome

Research Areas:  

Cancer

AA76-lipid (Compound aa76) is a compound with a C-terminal arginine and histidine. AA76-lipid can be used to prepare pancreas-targeted lipid nanoparticles AH-LNP. After assembling with proteins, the increased size of AH-LNP promotes Capsule-filter-mediated selective accumulation in the pancreas and receptor-mediated endocytosis, thereby enhancing pancreas-targeting ability. AA76-lipid enables highly pancreas-selective delivery of mRNA. AA76-lipid can be used in the research of pancreatic cancer .
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