21 Results for "

corylifolia

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "corylifolia" in MCE Product Catalog:

15
Neobavaisoflavone
Neobavaisoflavone
0 Images
15 Publications Verification
Referencia número: HY-N0720
No. CAS: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones

Target:  

Apoptosis DNA/RNA Synthesis

Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
loading...
    loading...
View All Sizes
13
Bavachin
Bavachin
0 Images
13 Cited Publications
Referencia número: HY-N0233
No. CAS: 19879-32-4
Synonyms: Corylifolin
Category:  

Flavonoids Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer

Target:  

Estrogen Receptor/ERR

Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
loading...
    loading...
View All Sizes
10
Isobavachalcone
Isobavachalcone
0 Images
10 Cited Publications
Referencia número: HY-13065
No. CAS: 20784-50-3
Pureza:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Plants Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
loading...
    loading...
View All Sizes
6
Isobavachin
Isobavachin
0 Images
6 Cited Publications
Referencia número: HY-N0762
No. CAS: 31524-62-6
Category:  

Flavonoids Neurological Disease Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Cytochrome P450 UGT p38 MAPK NF-κB NO Synthase COX Fc Receptor (FcR) RANKL/RANK Keap1-Nrf2 Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachin is an orally active, blood-brain barrier-penetrating prenylated flavonoid present in Psoralea corylifolia. Isobavachin inhibits human CYP2B6, CYP2C9, CYP2C19, UGT1A1, UGT1A9, and UGT2B7. Isobavachin suppresses MAPK activation, NF-κB nuclear translocation, overexpression of iNOS/COX-2, FcεRI-mediated signaling pathways, and RANKL-induced osteoclastogenesis. Isobavachin induces autophagy, cytotoxicity, neuronal differentiation, and NRF2 activation; it alleviates oxidative damage, inflammatory responses, apoptosis, iron accumulation, mitochondrial biogenesis, and mast cell degranulation. Isobavachin is applicable to research related to liver injury, inflammatory diseases, osteoporosis, liver cancer, prostate cancer, glioma, periodontitis-induced bone loss, and Alzheimer's disease .
loading...
    loading...
View All Sizes
13-Hydroxyisobakuchiol
13-Hydroxyisobakuchiol
0 Images
Referencia número: HY-N7506
No. CAS: 178765-49-6
Synonyms: Delta3,2-Hydroxylbakuchiol
Category:  

Monophenols Leguminosae Phenols Psoralea corylifolia L. Plants

Target:  

Monoamine Transporter Dopamine Transporter

13-Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) that can be isolated from Psoralea corylifolia (L.), is a potent selective monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50 = 0.58 μM) and norepinephrine transporter (NET) (IC50 = 0.69 μM) than for the serotonin transporter (SERT) (IC50 = 312.02 μM). 13-Hydroxyisobakuchiol increases the activity of intact mice and improves the decreased activity of reserpinized mice in vivo. 13-Hydroxyisobakuchiol can be used for the research of disorders such as Parkinson's disease and depression .
loading...
    loading...
View All Sizes
Psoralenoside
Psoralenoside
0 Images
Referencia número: HY-N7503
No. CAS: 905954-17-8
Category:  

Infection Leguminosae Simple Phenylpropanols Metabolic Disease Psoralea corylifolia L. Phenylpropanoids Plants Disease Research Fields

Target:  

Drug Intermediate Bacterial

Psoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections .
loading...
    loading...
View All Sizes
Isopsoralenoside
Isopsoralenoside
0 Images
Referencia número: HY-N7504
No. CAS: 905954-18-9
Category:  

Infection Leguminosae Ketones, Aldehydes, Acids Metabolic Disease Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Bacterial Reactive Oxygen Species (ROS)

Isopsoralenoside is a benzofuran glycoside and coumarin-derived compound. Isopsoralenoside exists in the dried mature fruits of Psoralea corylifolia L., and acts as a metabolite precursor, toxicant and inducer, with estrogen-like, osteoblast proliferation-promoting, anti-tumor and antibacterial activities. Isopsoralenoside can be deglycosylated by intestinal flora to form isopsoralen. Isopsoralenoside induces oocyte death in zebrafish, activates oxidative stress and cell death-related pathways in zebrafish follicles, and is the main effector substance responsible for the reproductive toxicity induced by Fructus Psoraleae. Isopsoralenoside can be used in studies related to reproductive toxicity (ovarian dysfunction, follicular atresia, impaired fertility) .
loading...
    loading...
View All Sizes
Furano(2'',3'',7,6)-4'-hydroxyflavanone
Furano(2'',3'',7,6)-4'-hydroxyflavanone
0 Images
Referencia número: HY-N9184
No. CAS: 1454619-70-5
Category:  

Flavonoids Leguminosae Flavonones Psoralea corylifolia L. Plants

Target:  

Others

Furano(2'',3'',7,6)-4'-hydroxyflavanone is a Flavonoids product that can be isolated from the seeds of Psoralea corylifolia. .
loading...
    loading...
View All Sizes
Psoracorylifol C
Psoracorylifol C
0 Images
Referencia número: HY-N10820
No. CAS: 879290-99-0
Category:  

Microorganisms Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Bacterial

Psoracorylifol C is a natural product. Psoracorylifol C has important activity against Helicobacter pylori. Psoracorylifol C can be isolated from the seeds of Psoralea corylifolia .
loading...
    loading...
View All Sizes
Neobavaisoflavone (Standard)
Neobavaisoflavone (Standard)
0 Images
Referencia número: HY-N0720R
No. CAS: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Isoflavones

Target:  

Reference Standards Apoptosis DNA/RNA Synthesis

Neobavaisoflavone (Standard) is the analytical standard of Neobavaisoflavone. This product is intended for research and analytical applications. Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
loading...
    loading...
View All Sizes
Psoralenoside (Standard)
Psoralenoside (Standard)
0 Images
Referencia número: HY-N7503R
No. CAS: 905954-17-8
Category:  

Leguminosae Simple Phenylpropanols Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Reference Standards Histamine Receptor Calcium Channel Calmodulin

Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
loading...
    loading...
View All Sizes
Bavachromene
Bavachromene
0 Images
Referencia número: HY-121236
No. CAS: 41743-38-8
Category:  

Flavonoids Chalcones Leguminosae Other Diseases Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Others

Bavachromene is a chromenochalcone from the seeds of Psoralea corylifolia with estrogenic activities .
loading...
    loading...
View All Sizes
Psoralea corylifolia polysaccharides
Psoralea corylifolia polysaccharides
0 Images
Referencia número: HY-N21465
Category:  

Leguminosae Psoralea corylifolia L. Extract Plants

Target:  

Others

Psoralea corylifolia polysaccharide is a polysaccharide derived from Psoralea corylifolia.
loading...
    loading...
View All Sizes
Bavachin (Standard)
Bavachin (Standard)
0 Images
Referencia número: HY-N0233R
No. CAS: 19879-32-4
Synonyms: Corylifolin (Standard)
Category:  

Flavonoids Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants

Target:  

Reference Standards Estrogen Receptor/ERR

Bavachin (Standard) is the analytical standard of Bavachin. This product is intended for research and analytical applications. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
loading...
    loading...
View All Sizes
Bakuchicin
Bakuchicin
0 Images
Referencia número: HY-N11698
No. CAS: 4412-93-5
Synonyms: Allopsoralen
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Topoisomerase

Bakuchicin (Allopsoralen) is a compound that can be found in Psoralea corylifolia. It has certain inhibitory activity against topoisomerase II. In the cell model infected with Simian virus 40 (SV40), the IC50 of Bakuchicin against topoisomerase II is 404 μM. Bakuchicin can be used in the research of the anti-infection field .
loading...
    loading...
View All Sizes
Isobavachalcone (Standard)
Isobavachalcone (Standard)
0 Images
Referencia número: HY-13065R
No. CAS: 20784-50-3
Synonyms: Corylifolinin (Standard); Isobacachalcone (Standard)
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Glycyrrhiza uralensis Fisch.

Target:  

Reference Standards Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Standard) is the analytical standard of Isobavachalcone. This product is intended for research and analytical applications. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
loading...
    loading...
View All Sizes
Psoracorylifol A
Psoracorylifol A
0 Images
Referencia número: HY-N19926
No. CAS: 879290-97-8
Category:  

Monophenols Leguminosae Phenols Psoralea corylifolia L. Plants Compositae Tephrosia candida DC.

Target:  

Bacterial

Psoracorylifol A is a Helicobacter pylori inhibitor present in the seeds of Psoralea corylifolia, with an MIC of 25 μg/mL against H. pylori strain SS1 and the metronidazole-resistant strain ATCC 43504. Psoracorylifol A is applicable to research related to Helicobacter pylori infection .
loading...
    loading...
View All Sizes
Malaytea scurfpea extract
Malaytea scurfpea extract
0 Images
Referencia número: HY-N20381
Category:  

Extract

Target:  

Fungal

Malaytea scurfpea extract is an extract of Psoralea corylifolia L., which has antifungal activity.
loading...
    loading...
View All Sizes
Isoficusin A
Isoficusin A
0 Images
Referencia número: HY-N9242
No. CAS: 1914963-20-4
Category:  

Flavonoids Leguminosae Psoralea corylifolia L. Plants Fabaceae

Target:  

Others

Isoficusin A is a Flavonoids product that can be isolated from the seeds of Psoralea corylifolia Linn. .
loading...
    loading...
View All Sizes
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen
0 Images
Referencia número: HY-N9288
No. CAS: 151121-39-0
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Others

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Psoralea corylifolia L. .
loading...
    loading...
View All Sizes
Assay Types