905954-18-9
Chemical Structure
Isopsoralenoside
- CAS No.: 905954-18-9
- Formula:C17H18O9
- Molecular Weight:366.32
IUPAC Name: (Z)-3-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzofuran-5-yl)acrylic acid
InChIKey: CAMYXILYLXYDFE-MIVOEOINSA-N
SMILES: O=C(O)/C=C\C1=CC=C(OC=C2)C2=C1O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O
Biological Activity: Isopsoralenoside is a benzofuran glycoside and coumarin-derived compound. Isopsoralenoside exists in the dried mature fruits of Psoralea corylifolia L., and acts as a metabolite precursor, toxicant and inducer, with estrogen-like, osteoblast proliferation-promoting, anti-tumor and antibacterial activities. Isopsoralenoside can be deglycosylated by intestinal flora to form isopsoralen. Isopsoralenoside induces oocyte death in zebrafish, activates oxidative stress and cell death-related pathways in zebrafish follicles, and is the main effector substance responsible for the reproductive toxicity induced by Fructus Psoraleae. Isopsoralenoside can be used in studies related to reproductive toxicity (ovarian dysfunction, follicular atresia, impaired fertility)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isopsoralenoside | 98.57% | Isopsoralenoside is a benzofuran glycoside and coumarin-derived compound. Isopsoralenoside exists in the dried mature fruits of Psoralea corylifolia L., and acts as a metabolite precursor, toxicant and inducer, with estrogen-like, osteoblast proliferation-promoting, anti-tumor and antibacterial activities. Isopsoralenoside can be deglycosylated by intestinal flora to form isopsoralen. Isopsoralenoside induces oocyte death in zebrafish, activates oxidative stress and cell death-related pathways in zebrafish follicles, and is the main effector substance responsible for the reproductive toxicity induced by Fructus Psoraleae. Isopsoralenoside can be used in studies related to reproductive toxicity (ovarian dysfunction, follicular atresia, impaired fertility). | ||||||||||||||||||||
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- [1]. Wang YF, et al. A UPLC-MS/MS method for in vivo and in vitro pharmacokinetic studies of psoralenoside, isopsoralenoside, psoralen and isopsoralen from Psoralea corylifolia extract. Journal of ethnopharmacology. 2014;151(1):609-17. [Content Brief]
- [2]. Xu Q, et al. Comprehensive studies of plasma pharmacokinetic and bone tissue distribution in rats to elucidate pharmacodynamic material basis of Psoraleae Fructus treating osteoporosis. Journal of ethnopharmacology. 2026 Apr 06;360:121145. [Content Brief]
- [3]. Shen X, et al. Reproductive toxicity of Fructus Psoraleae in zebrafish: material basis and implications for clinical safety dosing. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2026 Jun;155:158194. [Content Brief]
Keywords
