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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
131 Results for "
covalent labeling
" in MedChemExpress (MCE) Product Catalog:
Products (131)
131 Results for "covalent labeling" in MCE Product Catalog:
10
10 Publications Verification
Cat. No.: HY-D0056
CAS No.: 150206-05-6
8
8 Cited Publications
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
2
2 Cited Publications
Cat. No.: HY-W053709A
CAS No.: 1416711-59-5
Synonyms: (4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine (monohydrochloride); Tetrazine-NH2 monohydrochloride
Target:
Research Areas:
Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition . Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
2
2 Cited Publications
Cat. No.: HY-D1806
Product Concentration: 0.8 mg/mL
1
1 Cited Publications
1
1 Cited Publications
Cat. No.: HY-D2171A
1
1 Cited Publications
Cat. No.: HY-D1808
Product Concentration: 0.8 mg/mL
1
1 Cited Publications
Synonyms: 15d-PGJ2-d4; 15-Deoxy-Δ12,14-PGJ2-d4
1
1 Cited Publications
Cat. No.: HY-112624I
CAS No.: 9004-54-0
Synonyms: Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
Cat. No.: HY-79647
CAS No.: 82911-69-1
Synonyms: N-(Fmoc-oxy)succinimide
Cat. No.: HY-164899
CAS No.: 2765091-45-8
Synonyms: 2-aminopyridine-3-carboxylic acid imidazolide
Target:
Research Areas:
2A3 (2-aminopyridine-3-carboxylic acid imidazolide) is a covalent probe reagent for Selective 2'-Hydroxyl Acylation analyzed by Primer Extension (SHAPE) that targets the RNA ribose 2'-OH group. 2A3 efficiently permeates the biological membranes of Gram-negative bacteria, Gram-positive bacteria, and mammalian cells. 2A3 exhibits no base bias and specifically labels conformationally flexible, unpaired regions within RNA.
2A3 forms covalent adducts by acylating the 2'-OH groups of flexible RNA residues. When combined with SHAPE-MaP (mutational profiling) sequencing technology, these modification sites are converted into detectable mutational signals, thereby accurately reflecting local RNA backbone flexibility and base-pairing status. 2A3 is primarily utilized in molecular biology and transcriptomics research, including the resolution of RNA structuromes in living cells, the study of RNA folding regulatory mechanisms, and the investigation of non-coding RNA functions .
Synonyms: 5-TMRIA
Cat. No.: HY-15772S1
CAS No.: 2254100-49-5
Synonyms: AZD-9291-13C,d3; Mereletinib-13C,d3
Cat. No.: HY-W998680
CAS No.: 2228857-33-6
Synonyms: 5-FITC-Maleimide
Cat. No.: HY-177554
CAS No.: 2724919-69-9
Target:
Research Areas:
KB05yne is a site-selective, alkyne-functionalized electrophilic "probe" fragment probe designed for covalent ligand discovery, with preferential reactivity toward specific cysteine residues in proteins. KB05yne strongly labels wild-type target proteins (e.g., CDKN2AIP, HPCAL1) but does not label their cysteine-to-alanine mutants, confirming site-specific cysteine reactivity. KB05yne can be used for the discovery and optimization of site-specific covalent ligands, and is applicable to proteins with diverse structures and functions, especially in studies targeting cysteine residues in cancer-related or difficult-to-purify proteins .
Cat. No.: HY-D1390A
CAS No.: 2130955-10-9
Synonyms: Sulfo-cyanine5 maleimide
Target:
Research Areas:
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
Cat. No.: HY-D0967
CAS No.: 146368-15-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
