1 Result for "

dapt+inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "dapt+inhibitor" in MCE Product Catalog:

169
169 Cited Publications
Cat. No.: HY-13027
CAS No.: 208255-80-5
Purity:  99.97%
Synonyms: GSI-IX
DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and 42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment .
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