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Results for "

deacetylate

" in MedChemExpress (MCE) Product Catalog:

37

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11

Biochemical Assay Reagents

6

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5

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1

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2144C
    Chitosan (≥95% deacetylated,viscosity 100-200 mPa.s)

    deacetylated chitin (≥95% deacetylated,viscosity 100-200 mPa.s); Poly(D-glucosamine) (≥95% deacetylated,viscosity 100-200 mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin) (≥95% deacetylated,viscosity 100-200 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi .
    Chitosan (≥95% deacetylated,viscosity 100-200 mPa.s)
  • HY-B2144A
    Chitosan (MW 150000)
    2 Publications Verification

    deacetylated chitin (MW 150000); Poly(D-glucosamine) (MW 150000)

    		 Environmental Pollutants Fungal Bacterial Infection Cancer
    Chitosan (MW 150000) (Deacetylated chitin (MW 150000)) is a polycationic linear polysaccharide derived from chitin with the molecular weight of 150000. Chitosan is an versatile biomaterial because of its non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan also has antitumor, antibacterial, antifungal, and antioxidant activities .
    Chitosan (MW 150000)
  • HY-B2144B
    Chitosan (MW 30000)

    deacetylated chitin (MW 30000); Poly(D-glucosamine) (MW 30000)

    		 Environmental Pollutants Bacterial Fungal Infection Cancer
    Chitosan (MW 30000) (Deacetylated chitin (MW 30000)) is a polycationic linear polysaccharide derived from chitin with the molecular weight of 30000. Chitosan is an versatile biomaterial because of its non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan also has antitumor, antibacterial, antifungal, and antioxidant activities .
    Chitosan (MW 30000)
  • HY-14905
    Uridine triacetate

    Tri-O-acetyl uridine

    		 Drug Derivative Neurological Disease
    Uridine triacetate (Tri-O-acetyl uridine) is an orally active proagent of Uridine (HY-B1449). Uridine triacetate is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate is used for the research of 5-fluorouracil (5-FU) and capecitabine toxicity, or early-onset cardiac or central nervous system (CNS) .
    Uridine triacetate
  • HY-B2144E
    Chitosan (≥90% deacetylated, Low viscosity,<200mPa.s)

    deacetylated chitin (≥90% deacetylated, Low viscosity,<200mPa.s); Poly(D-glucosamine) (≥90% deacetylated, Low viscosity,<200mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin) (≥90% deacetylated, Low viscosity,<200mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi .
    Chitosan (≥90% deacetylated, Low viscosity,<200mPa.s)
  • HY-148507
    GSK1790627
    1 Publications Verification

    		 MEK Cancer
    GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis .
    GSK1790627
  • HY-N1511
    Ganoderic acid D
    2 Publications Verification

    		 Sirtuin Apoptosis Cancer
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D
  • HY-B2144K
    Chitosan (≥85% deacetylated, viscosity>90 mPa.s, MW 15000)

    deacetylated chitin (≥85% deacetylated, viscosity>90 mPa.s, MW 15000); Poly(D-glucosamine) (≥85% deacetylated, viscosity>90 mPa.s, MW 15000)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Inflammation/Immunology Cancer
    Chitosan (Deacetylated chitin) (≥85% deacetylated, viscosity>90 mPa.s, MW 15000) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi .
    Chitosan (≥85% deacetylated, viscosity>90 mPa.s, MW 15000)
  • HY-B2144J
    Chitosan (≥90% deacetylated,viscosity 650-700 mPa.s)

    deacetylated chitin (≥90% deacetylated,viscosity 650-700 mPa.s); Poly(D-glucosamine) (≥90% deacetylated,viscosity 650-700 mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 650-700 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated, viscosity 650-700 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing .
    Chitosan (≥90% deacetylated,viscosity 650-700 mPa.s)
  • HY-B2144G
    Chitosan (≥80% deacetylated, High viscosity,>400mPa.s)

    deacetylated chitin (≥80% deacetylated, High viscosity,>400mPa.s); Poly(D-glucosamine) (≥80% deacetylated, High viscosity,>400mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin; Poly(D-glucosamine)) (≥80% deacetylated, High viscosity,>400mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi .
    Chitosan (≥80% deacetylated, High viscosity,>400mPa.s)
  • HY-B2144F
    Chitosan (≥80% deacetylated, Medium viscosity,200-400mPa.s)

    deacetylated chitin (≥80% deacetylated, Medium viscosity,200-400mPa.s); Poly(D-glucosamine) (≥80% deacetylated, Medium viscosity,200-400mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin; Poly(D-glucosamine)) (≥80% deacetylated, Medium viscosity,200-400mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi .
    Chitosan (≥80% deacetylated, Medium viscosity,200-400mPa.s)
  • HY-17569
    Difluprednate

    		Phospholipase Inflammation/Immunology
    Difluprednate is a glucocorticoid receptor (GC receptor) agonist with a Ki of 0.78 nM. Difluprednate's active metabolite 21-deacetylated difluprednate (DFB) is a competitive agonist of GC receptors with a Ki of 0.061 nM. Difluprednate binds to GC receptors through metabolism to DFB, regulating the transcription of inflammatory mediator genes, thereby exerting anti-inflammatory activity. Difluprednate can be used for research related to ocular inflammation, such as postoperative inflammation, anterior uveitis, etc .
    Difluprednate
  • HY-13423
    Tenovin-1
    5 Publications Verification

    		 MDM-2/p53 Dihydroorotate Dehydrogenase Sirtuin Autophagy Cancer
    Tenovin-1, a p53 activator, protects p53 from MDM2-mediated degradation. Tenovin-1 acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also a dihydroorotate dehydrogenase (DHODH) inhibitor .
    Tenovin-1
  • HY-W013172
    Norgestimate

    		Progesterone Receptor Endocrinology
    Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norgestimate
  • HY-P2161B
    TAK-683 acetate
    4 Publications Verification

    		 Kisspeptin Receptor Cancer
    TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
    TAK-683 acetate
  • HY-B2144H
    Chitosan hydrochloride (80%-90% deacetylated)

    Chitosan HCl (80%-90% deacetylated)

    		 Bacterial Fungal Infection
    Chitosan hydrochloride 80%-90% deacetylated (Chitosan HCl 80%-90% deacetylated) is the deacetylated, hydrocholoride form of chitosan. Chitosan hydrochloride 80%-90% deacetylated is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan hydrochloride 80%-90% deacetylated is utilized in agriculture, water treatment and pharmaceutical aspects .
    Chitosan hydrochloride (80%-90% deacetylated)
  • HY-19745A
    N-deacetylated BMS-202
    1 Publications Verification

    		 PD-1/PD-L1 Cancer
    N-deacetylated BMS-202 is the deacetylated of BMS-202. BMS-202 is an inhibitor of the PD-1/PD-L1 interaction, mainly used for cancer treatment.
    N-deacetylated BMS-202
  • HY-117006
    E1231
    1 Publications Verification

    1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one

    		 Sirtuin Cardiovascular Disease
    E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE -/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases .
    E1231
  • HY-130538
    1-Naphthohydroxamic acid
    2 Publications Verification

    		 HDAC Cancer
    1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity .1-Naphthohydroxamic acid can induce tubulin acetylation .
    1-Naphthohydroxamic acid
  • HY-P5544
    M-TriDAP

    N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid

    		 NOD-like Receptor (NLR) Others
    M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .
    M-TriDAP
  • HY-B2144M
    Chitosan (85%~90% deacetylated,mushroom)

    		Biochemical Assay Reagents Infection Cancer
    Chitosan (85%-90% deacetylated,mushroom) is a polysaccharide obtained by deacetylating chitin from mushroom .
    Chitosan (85%~90% deacetylated,mushroom)
  • HY-B2144I
    Chitosan (≥90% deacetylated,viscosity 10 mPa.s)

    deacetylated chitin (≥90% deacetylated,viscosity 10 mPa.s); Poly(D-glucosamine) (≥90% deacetylated,viscosity 10 mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial Fungal Infection Cancer
    Chitosan (Deacetylated chitin) (≥90% deacetylated,viscosity 10 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated,viscosity 10 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing .
    Chitosan (≥90% deacetylated,viscosity 10 mPa.s)
  • HY-B2144L
    Chitosan (≥95% deacetylated,mushroom)

    		Biochemical Assay Reagents Infection Cancer
    Chitosan (≥95% deacetylated,mushroom) is a polysaccharide obtained by deacetylating chitin from mushroom .
    Chitosan (≥95% deacetylated,mushroom)
  • HY-B2144N
    Chitosan (≥98% deacetylated,mushroom)

    		Biochemical Assay Reagents Infection Cancer
    Chitosan (≥98% deacetylated,mushroom) is a biochemical reagent that can be used as a flocculant, protein precipitant, encapsulation agent, and aqueous thickener .
    Chitosan (≥98% deacetylated,mushroom)
  • HY-P2161
    TAK-683

    		Kisspeptin Receptor Cancer
    TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
    TAK-683
  • HY-P2115
    Ramorelix

    		GnRH Receptor Cancer
    Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .
    Ramorelix
  • HY-N1511R
    Ganoderic acid D (Standard)

    		Reference Standards Sirtuin Apoptosis Cancer
    Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D (Standard)
  • HY-N13082
    Deacetylescin Ia

    		Others Metabolic Disease
    Deacetylescin Ia (compound 12) is a deacetylated compound with anti-hyperglycemic effects that can be extracted from the debittered Aesculus and deacetylated at the C-22 position. Deacetylescin Ia (100 mg/kg) can inhibit blood glucose elevation in mouse glucose tolerance tests .
    Deacetylescin Ia
  • HY-130201
    Deacetylsaptomycin D

    		Drug Derivative Cancer
    Deacetylsaptomycin D is a deacetylated saptomycin with in vitro antitumor activity. Deacetylsaptomycin D inhibits the growth of mouse methoxy-A fibrosarcoma cells .
    Deacetylsaptomycin D
  • HY-115420
    1-β-D-Glucosylsphingadienine (d18:2 (4E8E))

    		Drug Metabolite Cardiovascular Disease
    1-β-D-Glucosylsphingadienine (d18:2 (4E8E)) is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides .
    1-β-D-Glucosylsphingadienine (d18:2 (4E8E))
  • HY-105516
    E5090

    		Interleukin Related Inflammation/Immunology
    E5090 is an orally active inhibitor of IL-1 generation which is converted in vivo into the pharmacologically active deacetylated form (DA-E5090). E5090 can be utilized in immunology research .
    E5090
  • HY-137934
    Deacetylforskolin

    7-Deacetylforskolin

    		 Endogenous Metabolite Cardiovascular Disease
    Deacetylforskolin is a deacetylated derivative of forskolin (HY-15371) that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity .
    Deacetylforskolin
  • HY-N11648
    Ganoderic acid T1

    		Apoptosis Caspase Inflammation/Immunology Cancer
    Ganoderic acid T1 is a deacetylated derivative of Ganoderic acid T. Ganoderic acid T1 attenuates antioxidant defense system and induces apoptosis of cancer cells. Ganoderic acid T1 decreases mitochondrial membrane potential and activates caspase-9 and caspase-3, to trigger apoptosis. Ganoderic acid T1 also increases the generation of intracellular ROS to produce pro-oxidant activities and cytotoxicity .
    Ganoderic acid T1
  • HY-P5544A
    M-TriDAP TFA

    N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA

    		 NOD-like Receptor (NLR) Others
    M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .
    M-TriDAP TFA
  • HY-P2161A
    TAK-683 TFA

    		Kisspeptin Receptor Cancer
    TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
    TAK-683 TFA
  • HY-117921
    DA-E 5090

    		Interleukin Related Inflammation/Immunology
    DA-E 5090 is an orally effective inhibitor of IL-1 production that can be converted into a pharmacologically active deacetylated form (DA-E5090) in vivo. In this study, the effects of DA-E5090 on IL-1 production in vitro were examined by LPS-stimulated human monocytes. The results showed that DA-E5090 could dose-dependently inhibit the production of IL-1α and IL-1β (1-10 μM) by LPS-stimulated human monocytes, as determined by LAF assay and ELISA. Northern blotting analysis showed that DA-E5090 inhibited the transcription of IL-1α and IL-1β mRNA.
    DA-E 5090
  • HY-P2859A
    Chitosanase, Streptomyces griseus

    		Biochemical Assay Reagents Metabolic Disease
    Chitosanase, Streptomyces griseus (EC 3.2.1.132) catalyzes the endohydrolysis of β (1,4) linkages between N-acetyl-D-glucosamine and D-glucosamine residues in partially deacetylated chitosan. Chitosanase, Streptomyces griseus (EC 3.2.1.132) is capable of hydrolyzing both chitosan and carboxymethyl cellulose.
    Chitosanase, Streptomyces griseus

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