871701-87-0
871701-87-0
Chemical Structure
GSK1790627
- CAS No.: 871701-87-0
- Formula:C24H21FIN5O3
- Molecular Weight:573.36
IUPAC Name: 1-(3-aminophenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione
InChIKey: JHOKCEWWVHBOFH-UHFFFAOYSA-N
SMILES: O=C1N(C2=CC=CC(N)=C2)C(C(C(N1C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C(C)C5=O
Biological Activity: GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK1790627 | 99.08% | GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-10999RTrametinib (Standard) -
Similarity Score 0.85
HY-179909MEK-IN-9 -
Similarity Score 0.84
HY-153181Trametiglue -
Similarity Score 0.84
HY-10999ATrametinib (DMSO solvate) -
Similarity Score 0.78
HY-10999S2Trametinib-13C,d3 -
Similarity Score 0.61
HY-126048JTP-70902 -
Similarity Score 0.53
HY-181571PDE4-IN-33 -
Similarity Score 0.49
HY-182292SARS-CoV-2 3CLpro-IN-37 -
Similarity Score 0.48
HY-142478KRAS G12C inhibitor 29 -
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