GSK1790627
Based on 1 publication(s) in Google Scholar
GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis.
For research use only. We do not sell to patients.
- Purity: 99.08%
- CAS No.: 871701-87-0
- Formula: C24H21FIN5O3
- Molecular Weight:573.36
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Immunology/Inflammation Compound Library
HY-L007
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Kinase Inhibitor Library
HY-L009
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MAPK Compound Library
HY-L010
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HY-L025
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HY-L039
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Oxygen Sensing Compound Library
HY-L045
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Ferroptosis Compound Library
HY-L051
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HY-L087
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HY-L088
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HY-L101
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HY-L103
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HY-L139
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HY-L164
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HY-L001V
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HY-L226
Publications Citing Use of MedChemExpress (MCE) GSK1790627
MoreAll MEK Isoforms
More
Biological Activity
Chemical Information
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CAS No. 871701-87-0
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Appearance Solid
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Molecular Weight 573.36
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Formula C24H21FIN5O3
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Color White to off-white
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SMILES
O=C1N(C2=CC=CC(N)=C2)C(C(C(N1C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C(C)C5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 10 mg/mL (17.44 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : 10 mg/mL (17.44 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / DMF | 1 mM | 1.7441 mL | 8.7205 mL | 17.4410 mL | 43.6026 mL |
| 5 mM | 0.3488 mL | 1.7441 mL | 3.4882 mL | 8.7205 mL | |
| 10 mM | 0.1744 mL | 0.8721 mL | 1.7441 mL | 4.3603 mL | |
| 15 mM | 0.1163 mL | 0.5814 mL | 1.1627 mL | 2.9068 mL |
GSK1790627 Related Classifications
HY-148507 Related Classifications
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