62 Results for "

desethyl

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "desethyl" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-17620
CAS No.: 149709-44-4
Synonyms: desethyl Sacubitril; LBQ-657
Target:  

Neprilysin

Research Areas:  

Neurological Disease

Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
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6
6 Cited Publications
Cat. No.: HY-10873
CAS No.: 356068-97-8
Purity:  99.90%
Synonyms: SU-12662
Target:  

Drug Metabolite

Research Areas:  

Cancer

N-Desethyl Sunitinib (SU-12662) is a metabolite of Sunitinib (HY-10255A). N-Desethyl Sunitinib serves as a good transport substrate for human ABCB1, ABCG2 and murine ABCG2 .
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6
6 Cited Publications
Cat. No.: HY-138813
Purity:  99.14%
Synonyms: SU-12662 hydrochloride
Target:  

Drug Metabolite

Research Areas:  

Cancer

N-Desethyl Sunitinib (SU-12662) (hydrochloride) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively .
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2
2 Cited Publications
Cat. No.: HY-135811A
CAS No.: 247912-76-1
Purity:  99.72%
Research Areas:  

Infection

Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity .
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2
2 Cited Publications
Cat. No.: HY-135811
CAS No.: 1476-52-4
Research Areas:  

Infection

Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .
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1
1 Cited Publications
Cat. No.: HY-128554
CAS No.: 79352-78-6
Purity:  99.98%
Target:  

Parasite

Research Areas:  

Infection

N-Desethyl amodiaquine is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine can be used for the research of malaria .
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1
1 Cited Publications
Cat. No.: HY-128554A
CAS No.: 79049-30-2
Purity:  99.45%
Target:  

Parasite

Research Areas:  

Infection

N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria .
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Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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Cat. No.: HY-128554S
CAS No.: 1173023-19-2
Purity:  ≥98.0%
N-Desethyl amodiaquine-d5 is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively .
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Cat. No.: HY-17620S
Synonyms: desethyl Sacubitril-d4; LBQ-657-d4
Sacubitrilat-d4 is the deuterium labeled Sacubitrilat. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor .
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Cat. No.: HY-W004360
CAS No.: 212321-78-3
Synonyms: desethyl Dabigatran Etexilate
BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate.
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Cat. No.: HY-146269
CAS No.: 103816-16-6
Target:  

Drug Metabolite

Research Areas:  

Cancer

11-Desethyl Irinotecan is a camptothecin (CPT) analog and one of the metabolites of irinotecan. It is promising for cancer research .
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Cat. No.: HY-128554S1
CAS No.: 1216894-33-5
Purity:  98.76%
N-Desethyl amodiaquine-d5 dihydrochloride is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively .
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Cat. No.: HY-10873S
CAS No.: 1217247-62-5
N-Desethyl Sunitinib-d5 is the deuterium labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively .
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Cat. No.: HY-136445S
CAS No.: 1219798-52-3
Synonyms: desethylterbuthylazine-d9
Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl . Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide) .
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Cat. No.: HY-P3066
CAS No.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
Target:  

Vasopressin Receptor

Research Areas:  

Metabolic Disease

SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
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Cat. No.: HY-136445
CAS No.: 30125-63-4
Synonyms: desethylterbuthylazine
Target:  

Drug Metabolite

Research Areas:  

Others

Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide) .
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Cat. No.: HY-17620R
CAS No.: 149709-44-4
Synonyms: desethyl Sacubitril (Standard); LBQ-657 (Standard)
Research Areas:  

Neurological Disease

Sacubitrilat (Standard) is the analytical standard of Sacubitrilat. This product is intended for research and analytical applications. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
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Cat. No.: HY-130353S
CAS No.: 1189960-80-2
Desethyl Amiodarone-d4 (hydrochloride) is the deuterium labeled Desethylamiodarone hydrochloride. Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM .
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Cat. No.: HY-135811R
CAS No.: 1476-52-4
Desethyl chloroquine (Standard) is the analytical standard of Desethyl chloroquine. This product is intended for research and analytical applications. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .
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