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Results for "

gamma radiation

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Natural
Products

1

Isotope-Labeled Compounds

1

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108694
    γ-Tocotrienol
    4 Publications Verification

    		 Endogenous Metabolite NF-κB Metabolic Disease Inflammation/Immunology
    γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment .
    γ-Tocotrienol
  • HY-A0087
    Octocrylene
    2 Publications Verification

    		 Environmental Pollutants PPAR Estrogen Receptor/ERR Biochemical Assay Reagents Cytochrome P450 Others
    Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
    Octocrylene
  • HY-A0104B
    HPMC (Type I,Viscosity:100mPa.s)

    Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)

    		 Environmental Pollutants Biochemical Assay Reagents Others
    HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process .
    HPMC (Type I,Viscosity:100mPa.s)
  • HY-117779
    DBIBB
    2 Publications Verification

    		 Apoptosis Endocrinology
    DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system .
    DBIBB
  • HY-W341499
    5-Formyl-2'-deoxyuridine

    		Endogenous Metabolite Others
    5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .
    5-Formyl-2'-deoxyuridine
  • HY-15276
    4-Aminonaphthalimide

    		PARP Cancer
    4-Aminonaphthalimide is a potent PARP inhibitor and potentiates the cytotoxicity of γ-radiation in cancer cells .
    4-Aminonaphthalimide
  • HY-108694R
    γ-Tocotrienol (Standard)

    		Reference Standards Endogenous Metabolite NF-κB Metabolic Disease Inflammation/Immunology
    γ-Tocotrienol (Standard) is the analytical standard of γ-Tocotrienol. This product is intended for research and analytical applications. γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a novel radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment .
    γ-Tocotrienol (Standard)
  • HY-118988
    CAY10506

    		PPAR Apoptosis Cancer
    CAY10506 is a PPARγ ligand that can induce cell death and ROS production in a PPARγ-dependent manner in vitro. CAY10506 exhibits radiosensitizing effects, enhancing γ-radiations-induced apoptosis and caspase-3-mediated poly (ADP-ribose) polymerase (PARP) cleavage. CAY10506 can be used in cancer research .
    CAY10506
  • HY-W654296
    Octocrylene-13C3

    		Isotope-Labeled Compounds PPAR Cytochrome P450 Biochemical Assay Reagents Estrogen Receptor/ERR Others
    Octocrylene- 13C3 is the 13C-labeled Octocrylene (HY-A0087). Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
    Octocrylene-13C3
  • HY-W666088
    (2-Phenylethyl)hydrazine dihydrochloride

    		Biochemical Assay Reagents Others
    (2-Phenylethyl)hydrazine (dihydrochloride) is a compound with protective effects against γ-radiation. At a dose of 60 mg/kg, it can increase the survival rate of mice exposed to γ-radiation .
    (2-Phenylethyl)hydrazine dihydrochloride
  • HY-N17390
    Citaldoxime

    		Endogenous Metabolite Fungal Infection
    Citaldoxime (Compound 7) is a γ-radiation-induced antifungal stress metabolite that can be found in Citrus plants .
    Citaldoxime

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