22 Results for "

gastrointestinal tissue

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "gastrointestinal tissue" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B1156
CAS No.: 38821-53-3
Synonyms: Cefradine; SQ-11436
Target:  

Bacterial Antibiotic TOPK

Research Areas:  

Infection Inflammation/Immunology

Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
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5
5 Cited Publications
Cat. No.: HY-128449
CAS No.: 75975-70-1
Purity:  91.53%
Synonyms: Cefradine monohydrate
Target:  

Bacterial Antibiotic TOPK

Research Areas:  

Infection Inflammation/Immunology

Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
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3
3 Cited Publications
Cat. No.: HY-W013494
CAS No.: 305-84-0
L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .
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3
3 Cited Publications
Cat. No.: HY-P0197
CAS No.: 86933-74-6
Synonyms: Substance K; Neurokinin α; Neuromedin L; NKA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
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3
3 Cited Publications
Cat. No.: HY-P0197A
CAS No.: 2828433-19-6
Synonyms: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
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1
1 Cited Publications
Cat. No.: HY-N0340
CAS No.: 149-64-4
Synonyms: Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide
Scopolamine butylbromide (Hyoscine butylbromide) is an orally active anticholinergic agent and spasmolytic. Scopolamine butylbromide binds with high affinity to rat cardiac M2 (Ki 83 nmol/L), hM2 (Ki 233 nmol/L), rat intestinal M3 (Ki 290 nmol/L) and hM3 (Ki 643 nmol/L) muscarinic receptors. Scopolamine butylbromide exerts a dose-dependent antagonistic effect on Carbachol-induced gastrointestinal smooth muscle spasm. Scopolamine butylbromide can be used for the research of abdominal colic and pain associated with gastrointestinal spasm, functional abdominal pain, chronic gastropathy and gastric ulcer .
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1
1 Cited Publications
Cat. No.: HY-17509
CAS No.: 169590-41-4
Synonyms: SC 046; SC 46; SC 59046
Deracoxib (SC 046; SC 59046), an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas .
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Cat. No.: HY-P10735
CAS No.: 181591-59-3
Synonyms: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse)
Target:  

Lipase Apoptosis

Research Areas:  

Metabolic Disease

GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue .
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Cat. No.: HY-106327
CAS No.: 110205-60-2
Target:  

Motilin Receptor

Research Areas:  

Metabolic Disease

EM-523 is a motilin agonist and an erythromycin derivative. EM-523 has pED50 values of 8.19 and 6.08 for promoting contractions in rabbit small intestinal tissue and human duodenal tissue, respectively. EM-523 can be used in the research of gastrointestinal diseases .
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Cat. No.: HY-17509S
CAS No.: 2012598-48-8
Synonyms: SC 046-d3; SC 46-d3; SC 59046-d3
Deracoxib-d3 (SC 046-d3; SC 59046-d3) is the deuterium labeled Deracoxib (HY-17509). Deracoxib, an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas.
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Cat. No.: HY-145686
CAS No.: 1107710-62-2
Purity:  99.31%
AV023 is a potent inhibitor of ANKRD22. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells and indirectly activates the Wnt classical pathway, which helps the recovery of damaged gastrointestinal mucosal tissues in the body (extracted from patent CN111205231B) .
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Cat. No.: HY-N2304A
CAS No.: 116388-85-3
Target:  

Opioid Receptor

Research Areas:  

Inflammation/Immunology

Methyl-6-alpha-Naltrexol is a metabolite of Methylnaltrexone (MNTX). Methylnaltrexone is a selective mu-opioid receptor antagonist and functions as a peripherally acting receptor antagonist in tissues of the gastrointestinal tract .
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Cat. No.: HY-P3861
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Biotin-Neurokinin A is a biotinylated Neurokinin A (HY-P0197). Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
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Cat. No.: HY-B1156A
CAS No.: 57584-26-6
Synonyms: Cefradine sodium; SQ-11436 sodium
Target:  

Bacterial Antibiotic TOPK

Research Areas:  

Infection Inflammation/Immunology

Cephradine sodium is a broad-spectrum and orally active cephalosporin. Cephradine sodium is active against both gram-positive and gram-negative pathogens. Cephradine sodium is effective in eradicating most penicillinase-producing organisms. Cephradine sodium has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine sodium blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
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Cat. No.: HY-B1156R
CAS No.: 38821-53-3
Synonyms: Cefradine (Standard); SQ-11436 (Standard)
Cephradine (Standard) is the analytical standard of Cephradine. This product is intended for research and analytical applications. Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
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Cat. No.: HY-137263
CAS No.: 35775-65-6
Target:  

Antibiotic

Research Areas:  

Infection

Propionylmaridomycin is a macrolide antibiotic with antibacterial activity. Propionylmaridomycin is rapidly absorbed from the gastrointestinal tract and rapidly distributed to tissues. Propionylmaridomycin radioactivity levels in the liver, kidneys, and lungs were significantly higher than in plasma, while distribution to the brain was less. Propionylmaridomycin is excreted primarily through the feces, and the high fecal recovery rate is due to unabsorbed compounds and biliary excretion of compounds and their metabolites. Propionylmaridomycin exhibits the highest antibacterial activity in the lungs. Propionylmaridomycin is completely converted to several metabolites in rats, of which 4''-depropionyl-9-propionylmaridomycin was identified as the major metabolite .
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Cat. No.: HY-17509R
CAS No.: 169590-41-4
Synonyms: SC 046 (Standard); SC 46 (Standard); SC 59046 (Standard)
Deracoxib (SC 046; SC 59046) (Standard) is the analytical standard of Deracoxib (HY-17509). This product is intended for research and analytical applications. Deracoxib, an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas
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Cat. No.: HY-W703540
CAS No.: 1794780-24-7
Synonyms: SC 046-d4; SC 46-d4; SC 59046-d4
Deracoxib-d4 (SC 046-d4; SC 59046--d4) is deuterium labeled Deracoxib (HY-17509). Deracoxib, an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas.
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Cat. No.: HY-K0602

MCE Alcian Blue Staining Solution (pH 2.5) is commonly used for the detection of acidic mucopolysaccharides and mucins in histological studies. It is suitable for cartilage staining, visualization of mucin distribution, evaluation of intestinal metaplasia in gastrointestinal tissues, and the auxiliary identification of mucin-producing epithelial tumors.

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Cat. No.: HY-167182
CAS No.: 470695-03-5
PUMAi is a PUMA inhibitor that disrupts the interaction between PUMA and BCL-xL. PUMAi inhibits apoptosis, caspase-3 activation, WNT/NOTCH pathway activation, and DNA damage. PUMAi protects intestinal tissues in mice, promotes the growth of colonoids, and reduces chemotherapy-induced weight loss, gastrointestinal damage, and lethality. PUMAi alleviates acetaminophen-induced liver injury and cytoplasmic translocation of HMGB1 in mice. PUMAi can be used in studies related to gastrointestinal injury, intestinal injury, and liver injury .
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