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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
gastroprokinetic agent
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "gastroprokinetic agent" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-B0189B
CAS No.: 636582-62-2
Synonyms: TAK-370 citrate dihydrate; AS-4370 citrate dihydrate
Research Areas:
Mosapride (TAK-370) citrate dehydrate is a gastroprokinetic agent with 5-hydroxytryptamine4 receptor agonist activity and has been widely used in the research of a variety of gastrointestinal disorders. Mosapride citrate dihydrate potently inhibits Kv4.3 in a concentration-dependent manner with IC50 values of 15.2 μM . Mosapride citrate dihydrateselectively stimulates upper GI motility in vivo .
Cat. No.: HY-106780
CAS No.: 104775-36-2
Synonyms: DQ 2511
Target:
Research Areas:
Ecabapide (DQ 2511) is an orally active gastroprokinetic agent. Ecabapide can ameliorate gastric emptying of stroke-prone spontaneously hypertensive rat model. Ecabapide can be studied in research on autonomic nervous system disorder .
Cat. No.: HY-148846
CAS No.: 1161443-73-7
Target:
Research Areas:
Mosapride N-Oxide is a major active metabolite of Mosapride. Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Cat. No.: HY-U00071
CAS No.: 106707-51-1
Target:
Research Areas:
Dobupride is a novel gastroprokinetic agent.
Cat. No.: HY-B0189S1
CAS No.: 1246820-66-5
Cat. No.: HY-121467S
CAS No.: 2749427-97-0
Synonyms: Z-338-d6 free base; YM443-d6 free base
Cat. No.: HY-L121
427 compounds
5-HT receptors, also called Serotonin receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. These receptors are now classified into seven families, 5-HT1–7, comprising a total of 14 structurally and pharmacologically distinct mammalian 5-HT receptor subtypes. The 5-HT receptors influence various biological and neurological processes such as aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, andthermoregulation. The serotonin receptors are the target of a variety of pharmaceutical drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens.
MCE 5-HT Receptor Compound Library consists of 427 5-HT receptor inhibitors and activators, which can be used for neuropsychiatric disorders drugs discovery.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
