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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
hepcidin
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "hepcidin" in MCE Product Catalog:
64
64 Publications Verification
Synonyms: FG-4592
Roxadustat is an orally active hypoxia-inducible factor prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin .
6
6 Cited Publications
Cat. No.: HY-112220
CAS No.: 2095668-10-1
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VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of β-thalassemia .
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2 Cited Publications
Synonyms: GDP disodium salt
2
2 Cited Publications
Synonyms: GDP sodium, Type I, 96% (HPLC)
2
2 Cited Publications
Cat. No.: HY-P4373A
Research Areas:
1
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1
1
1 Cited Publications
Cat. No.: HY-P700634
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuhepcidin/HAMP, GST; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1
Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
Target:
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Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC50<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias .
Synonyms: INCB-000928; NBU-928
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Zilurgisertib (INCB-000928; NBU-928) is a selective ALK2 inhibitor with an IC50 value of 15 nM. Zilurgisertib inhibits SMAD1/5 phosphorylation with an IC50 value of 63 nM. Zilurgisertib inhibits hepcidin production and improve anemia. Zilurgisertib can be used in melanoma research .
Cat. No.: HY-P3494
CAS No.: 1356390-47-0
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Cat. No.: HY-177662
CAS No.: 2273007-95-5
Synonyms: IONIS-TMPRSS6-Lrx; ISIS 702843
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Sapablursen, an antisense oligonucleotide, is designed to reduce the production of TMPRSS6 resulting in increased expression of hepcidin, which is the key regulator of iron homeostasis. Sapablursen can be used in the research of blood diseases such as pol
Cat. No.: HY-P4373
CAS No.: 1676104-75-8
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Cat. No.: HY-P990617
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Cat. No.: HY-113066S1
Synonyms: GDP-13C10 dilithium
Cat. No.: HY-147278
CAS No.: 2646704-10-9
Synonyms: Divesiran; SLN124
Research Areas:
Manusiran (Divesiran) is a GalNac-siRNA targeting liver and transmembrane serine protease 6 (Serine protease 6). Manusiran increases hepatic Hepcidin synthesis and plasma levels by silencing TMPRSS6, a negative regulator of hepcidin production, and limits the availability of iron required for erythropoiesis. Combined use of Manusiran with Deferiprone (HY-B0568) reduces ineffective erythropoiesis and hepatic iron overload in a mouse model of β-thalassemia. Manusiran can be used for research on polycythemia vera, type 1 hereditary hemochromatosis, and β-thalassemia .
Cat. No.: HY-113066S
Purity: 98.20%
Synonyms: GDP-15N5 dilithium
Cat. No.: HY-113066AR
CAS No.: 7415-69-2
Synonyms: GDP disodium salt (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
