2 Results for "

hmeprin-α

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hmeprin-α" in MCE Product Catalog:

7
Actinonin
Actinonin
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7 Cited Publications
Cat. No.: HY-113952
CAS No.: 13434-13-4
Purity:  98.37%
Synonyms: (-)-Actinonin
Category:  

Infection Natural Products Microorganisms Marine natural products Disease Research Fields

Target:  

Aminopeptidase Bacterial MMP Apoptosis Antibiotic

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities .
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Actinonin (Standard)
Actinonin (Standard)
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Cat. No.: HY-113952R
CAS No.: 13434-13-4
Synonyms: (-)-Actinonin (Standard)
Category:  

Natural Products Microorganisms

Target:  

Reference Standards Aminopeptidase Bacterial MMP Apoptosis Antibiotic

Actinonin (Standard) is the analytical standard of Actinonin. This product is intended for research and analytical applications. Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
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