83 Results for "

human+serum

" in MedChemExpress (MCE) Product Catalog:
Products (83)

83 Results for "human+serum" in MCE Product Catalog:

4
Human serum albumin
Human serum albumin
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4 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: HSA
Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO −) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant Human Serum Albumin expressed in a microbial expression system.
1
GPDA
GPDA
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1 Cited Publications
Cat. No.: HY-16710
CAS No.: 65096-46-0
Synonyms: GPN; Glycylproline p-nitroanilide tosylate
GPDA (GPN; Glycylproline p-nitroanilide tosylate) is a chromogenic substrate of prolyl dipeptidyl aminopeptidase. GPDA is used to detect the activity of prolyl dipeptidyl aminopeptidase in human serum .
1
Complement C5-IN-1
Complement C5-IN-1
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1 Cited Publications
Cat. No.: HY-128342
CAS No.: 2365402-67-9
Purity:  99.14%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Compound C5-IN-1 (Compound 7) is a selective allosteric inhibitor of complement component protein C5. Compound C5-IN-1 prevents C5 from being cleaved by C5 convertase, inhibits the cleavage of C5 into C5a and C5b, and thus blocks the formation of membrane attack complex (MAC). Compound C5-IN-1 has an IC50 of 0.77 μM and 5 nM in 50% human whole blood and 2% human serum to block MAC deposition induced by zymosan, respectively. Compound C5-IN-1 can be used to study diseases related to complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
1
Dimethylmalonic acid
Dimethylmalonic acid
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1 Cited Publications
Cat. No.: HY-W007894
CAS No.: 595-46-0
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .
Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
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Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: HSA (Cell culture grade, Endotoxin<0.125 EU/mg)
Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO −) in the vascular wall, contributing to the reduction of blood pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
Ozoralizumab
Ozoralizumab
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Cat. No.: HY-P99796
CAS No.: 1167985-17-2
Synonyms: ATN-103; PF-5230896

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .
Insulin icodec
Insulin icodec
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
Recombinant Human Serum Albumin(rHSA)
Recombinant Human Serum Albumin(rHSA)
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Cat. No.: HY-150097
Purity:  ≥99.0%
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
5-Aminofluorescein
5-Aminofluorescein
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Cat. No.: HY-D0022
CAS No.: 3326-34-9
Synonyms: 5-AF
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .
Sonelokimab
Sonelokimab
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Cat. No.: HY-P99397
CAS No.: 1414386-05-2
Synonyms: ALX 0761; M 1095

Target:  

Interleukin Related MMP

Research Areas:  

Inflammation/Immunology

Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .
Vobarilizumab
Vobarilizumab
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Cat. No.: HY-P99385
CAS No.: 1628814-88-9
Synonyms: ALX-0061

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .
Canine Serum Albumin
Canine Serum Albumin
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Cat. No.: HY-NP002L
Canine Serum Albumin is a plasma protein derived from dogs. Canine Serum Albumin exhibits greater flexibility than human serum albumin and bovine serum albumin. Serum albumin is a multifunctional protein with exceptional ligand-binding capacity, which enables it to act as a transport molecule for various metabolites, drugs, nutrients, metals and other molecules .
7-Methoxyflavone
7-Methoxyflavone
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Cat. No.: HY-N8487
CAS No.: 22395-22-8
Category:  

Flavonoids Neurological Disease Leguminosae Flavones Zornia brasiliensis Plants Disease Research Fields Inflammation/Immunology

Target:  

Cytochrome P450

7-Methoxyflavone is a flavonoid compound that can be isolated from Zornia brasiliensis. 7-Methoxyflavone can bind to human serum albumin and is an aromatase inhibitor. 7-Methoxyflavone has peripheral analgesic and certain antitumor activities. 7-Methoxyflavone is effective against chemical pain but has no significant effect on thermal pain .
Donzakimig
Donzakimig
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Cat. No.: HY-P990735
CAS No.: 2765066-99-5
Synonyms: UCB-1381

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Donzakimig is a trispecific anti-IL-13/IL-22/HSA antibody. Donzakimig adopts a Fab-scFv-scFv structural format (without an Fc region), in which the Fab domain is linked to the scFv domains via a S (G4S)2 linker. Donzakimig binds to and inhibits the activities of IL-13 and IL-22, thereby blocking the signal transduction of these two cytokines. Donzakimig can extend its serum half-life by binding to human serum albumin, enhancing its in vivo stability and achieving long-acting efficacy. Donzakimig can be used in research on moderate-to-severe atopic dermatitis, moderate-to-severe asthma (especially eosinophilic type), psoriasis, inflammatory bowel disease, and other conditions .
Adenosine 3′-monophosphate
Adenosine 3′-monophosphate
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Cat. No.: HY-W587488
CAS No.: 84-21-9
Synonyms: 3′-AMP
Target:  

Nucleoside Antimetabolite/Analog Cyclic GMP-AMP Synthase

Research Areas:  

Cancer

Adenosine 3’-monophosphate (3’-AMP) is a nucleotide. Adenosine 3’-monophosphate is a cyclic AMP production agonist. Adenosine 3’-monophosphate increases cyclic AMP levels concentration-dependently in NG108-15 cells. Adenosine 3’-monophosphate can be used in the determination of acid phosphatase activity of human serum, which is estabilished as a laboratory procedure in the diagnosis of prostate cancer, metastatic mammary cancer and Gaucher’s disease. Adenosine 3’-monophosphate inhibits human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors .
Licarin A
Licarin A
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Cat. No.: HY-N2252
CAS No.: 51020-86-1
Synonyms: (+)-Licarin A
Category:  

Saururaceae Monophenols Neurological Disease Saururus chinensis (Lour.) Baill. Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

TNF Receptor Prostaglandin Receptor COX

Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
CCX662
CCX662
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Cat. No.: HY-167851
CAS No.: 1226686-54-9
Target:  

CXCR

Research Areas:  

Neurological Disease Cancer

CCX662 is a selective CXCR7 inhibitor with human IC50 values of 9 nM (buffer) and 18 nM (100% human serum), and rat IC50 of 14 nM (100% rat serum). CCX662 blocks CXCL12 binding to CXCR7, inhibits CXCR4-directed trans-endothelial migration of CXCR4 +/CXCR7 + cells. CCX662 can be used for the research of glioblastoma multiforme .
8-Bromoadenosine
8-Bromoadenosine
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Cat. No.: HY-W013195
CAS No.: 2946-39-6
Target:  

Nucleoside Antimetabolite/Analog

Research Areas:  

Cancer

8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. 8-Bromoadenosine can quench the intrinsic fluorescence of human serum albumin (HSA) through static quenching procedure. 8-Bromoadenosine can be used to synthesize adenosine phosphate, such as Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
Blue dextran (MW 70000)
Blue dextran (MW 70000)
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Cat. No.: HY-W134328E
CAS No.: 87915-38-6
Synonyms: Dextran blue (MW 70000)
Blue dextran (MW 70000) (Dextran blue (MW 70000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
Clopidogrel carboxylic acid
Clopidogrel carboxylic acid
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Cat. No.: HY-141749A
CAS No.: 144457-28-3
Synonyms: CLPM; SR 26334
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .
Assay Types