2. Apoptosis
  3. TNF Receptor
  4. Ozoralizumab

Ozoralizumab  (Synonyms: ATN-103)

Cat. No.: HY-P99796 Purity: 99.80%
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Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis.

For research use only. We do not sell to patients.

Ozoralizumab Chemical Structure

Ozoralizumab Chemical Structure

CAS No. : 1167985-17-2

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Based on 1 publication(s) in Google Scholar

Ozoralizumab Related Antibodies

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Description

Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis[1].

In Vitro

Ozoralizumab (ATN-103; 0-1000 pM; 48 h) has high TNFα-neutralizing potency in the L929 cell cytotoxicity assay with KD values of 20.2 pM and 16.1 pM for human TNFα and monkey TNFα, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ozoralizumab Related Antibodies
In Vivo

Ozoralizumab (ATN-103; 1 mg/kg; s.c.; Tg197 human TNF transgenic mice) inhibits arthritis and reduces arthritis scores[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Tg197 human TNF transgenic mice[1]
Dosage: 1 mg/kg
Administration: Subcutaneous injection
Result: Reduced the mean histopathologic score in the Tg197 mice.
Had ability to neutralize TNFα activity.
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Ozoralizumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.80%

COA (231 KB)

Handling Instructions (2659 KB)
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Ozoralizumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ozoralizumab1167985-17-2ATN-103ATN103ATN 103TNF ReceptorTumor Necrosis Factor ReceptorTNFRserum albuminL929 cellarthritisInhibitorinhibitorinhibit

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