62 Results for "

human EGF

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "human EGF" in MCE Product Catalog:

103
103 Publications Verification
Cat. No.: HY-P7109
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuEGF; Pro-epidermal growth factor; Urogastrone
Species:  
Source:  
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5
5 Cited Publications
Cat. No.: HY-P7109G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Pro-epidermal growth factor; EGF; Urogastrone
Species:  
Source:  
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3
3 Cited Publications
Cat. No.: HY-P7017
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuHB-EGF; HBEGF; Diphtheria toxin receptor; DTR
Species:  
Source:  
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3
3 Cited Publications
Cat. No.: HY-P7400
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuProheparin-binding EGF-like Growth Factor; DTR; DTS; HEGFL
Species:  
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P99041
CAS No.: 339177-26-3
Synonyms: ABX-EGF

Target:  

EGFR

Research Areas:  

Cancer

Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .
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1
1 Cited Publications
Cat. No.: HY-P72487
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Proheparin-binding EGF-like growth factor; HB-EGF; DT-R; DTS; HEGFL
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody; Cell growth inhibiting protein 40 antibody; Cell proliferation inducing protein 61 antibody; EGF R antibody; EGFR antibody; EGFR_human antibody; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody; Epidermal growth factor receptor antibody; erb-b2 receptor tyrosine kinase 1 antibody; ERBB antibody; ERBB1 antibody; Errp antibody; HER1 antibody; mENA antibody; NISBD2 antibody; Oncogen ERBB antibody; PIG61 antibody; Proto-oncogene c-ErbB-1 antibody; Receptor tyrosine protein kinase ErbB 1 antibody; Receptor tyrosine-protein kinase ErbB-1 antibody; SA7 antibody; Species antigen 7 antibody; Urogastrone antibody; v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody; wa2 antibody; Wa5 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC, mIHC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P9964
CAS No.: 906805-06-9
Synonyms: 11F8; IMC-11F8; LY3012211

Target:  

EGFR

Research Areas:  

Cancer

Necitumumab (11F8; IMC-11F8; LY3012211) is a human IgG monoclonal antibody directed against EGFR. Necitumumab binds to the EGF binding site of EGFR, blocks ligand binding, neutralizes ligand-induced EGFR phosphorylation and downstream signaling, induces EGFR internalization and degradation, and mediates antibody-dependent cellular cytotoxicity (ADCC) in EGFR-expressing cells. Necitumumab enhances antitumour activity in combination with Gemcitabine (HY-17026) and Cisplatin (HY-17394) in murine non-small-cell lung cancer xenograft models. Necitumumab can be used in research on cancers such as non-small cell lung cancer and colorectal cancer .
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Cat. No.: HY-P99155
CAS No.: 667901-13-5
Synonyms: 2F8; HUMAX-EGFR

Target:  

EGFR

Research Areas:  

Cancer

Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer .
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Cat. No.: HY-P10697A
Target:  

LDLR

Research Areas:  

Metabolic Disease

VH4127 TFA is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127 TFA specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR .
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Cat. No.: HY-101960A
CAS No.: 126433-07-6
Purity:  ≥99.0%
Synonyms: AG-183
Target:  

EGFR

Research Areas:  

Cancer

Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .
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Cat. No.: HY-N11262
CAS No.: 4281-28-1
Sudachitin is an orally active compound that potently inhibits mouse PDE1C and human PDE4B, with IC50 values of 5.0 μM and 15.0 μM, respectively. Sudachitin upregulates Sirt1 and PGC‑1α expression in skeletal muscle to regulate energy metabolism and promote mitochondrial biogenesis. Sudachitin improves lipid metabolism, glucose tolerance, insulin sensitivity, energy expenditure, and fatty acid β‑oxidation. Sudachitin activates p38MAPK signaling, induces HSP27 phosphorylation and caspase‑dependent apoptosis, and blocks EGF‑driven keratinocyte migration and proliferation. Sudachitin suppresses LPS‑induced TNF‑α, NO, and iNOS expression in macrophages and shows potent anti‑inflammatory activity. Sudachitin can be used for the research of metabolic syndrome, type 2 diabetes, and psoriasis. .
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Cat. No.: HY-RS04204
Research Areas:  

Others

EGF Human Pre-designed siRNA Set A contains three designed siRNAs for EGF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99155A
CAS No.: 667901-13-5

Target:  

EGFR

Research Areas:  

Cancer

Zalutumumab (powder) is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab (powder) binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab (powder) binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab (powder) can be used for the research of cancer .
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Cat. No.: HY-P99041B
CAS No.: 339177-26-3
Synonyms: ABX-EGF (powder)

Target:  

EGFR

Research Areas:  

Cancer

Panitumumab (ABX-EGF) (powder) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (powder) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (powder) can be used in the research of cancers, such as colon cancer .
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Cat. No.: HY-129510
CAS No.: 1346601-52-2
Target:  

EGFR Mitosis

Research Areas:  

Cancer

4-Methyl erlotinib, is a potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. 4-Methyl erlotinib potently inhibits EGF-mediated tumor cell mitosis by reducing EGFr-specific tyrosine phosphorylation. Using a mouse model of human tumor transplantation, 4-Methyl erlotinib demonstrated significant and sustained suppression of EGFr phosphotyrosine levels, resulting in significant growth inhibition of EGFr-dependent human cancers .
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Cat. No.: HY-P10697
Target:  

LDLR

Research Areas:  

Metabolic Disease

VH4127 is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127, bearing non-natural amino acid residues, specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR .
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Cat. No.: HY-155983
Research Areas:  

Cancer

E07 aptamer is an aptamer that targets human EGFR. E07 aptamer can compete with EGF for binding, binds to a novel epitope on EGFR. E07 aptamer binds to cells expressing EGFR, blocks receptor autophosphorylation, and prevents proliferation of tumor cells in three-dimensional matrices. E07 aptamer can be used for tomor disease research .
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Cat. No.: HY-101960
CAS No.: 122520-90-5
Synonyms: (Z)-AG-183
Target:  

EGFR

Research Areas:  

Others

(Z)-Tyrphostin A51 is the Z configuration of Lanoconazole A51. Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .
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Cat. No.: HY-176780
CAS No.: 2794979-74-9
Research Areas:  

Cancer

Gαi2-IN-1 is a Gαi2 inhibitor. Gαi2-IN-1 attenuates migration of prostate cancer cells. Gαi2-IN-1 can be used for the research of prostate cancer .
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