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Zalutumumab

(Synonyms: 2F8; HUMAX-EGFR)
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Based on 1 Customer Validation

Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer.

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  • Pureté: 98.34%
  • CAS No.: 667901-13-5
  • Masse moléculaire:146.52 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zalutumumab
  • Experimental Validation Results for Zalutumumab
  • Experimental Validation Results for Zalutumumab
  • Zalutumumab Chemical Structure
    Zalutumumab Chemical Structure
CAS No.: 667901-13-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human EGFR Protein (ECD, His Tag) can bind Zalutumumab. The EC50 for this effect is 5.92 ng/mL.

  • 1/16

    Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Zalutumumab (anti-ERBB1/EGFR/HER1) (HY-P99155). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1(K214R) kappa (HY-P99995). Black-Unlabelled control, cells without incubation with primary antibody.

  • Zalutumumab Chemical Structure
    1/16
  • Zalutumumab
  • Immobilized Human EGFR Protein (ECD, His Tag) can bind Zalutumumab. The EC50 for this effect is 5.92 ng/mL.
  • Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Zalutumumab (anti-ERBB1/EGFR/HER1) (HY-P99155). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1(K214R) kappa (HY-P99995). Black-Unlabelled control, cells without incubation with primary antibody.