Copy Link Print Information

Zalutumumab

(Synonyms: 2F8; HUMAX-EGFR)
Customer Review

Based on 1 Customer Validation

Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer.

For research use only. We do not sell to patients.

  • Purity: 98.34%
  • CAS No.: 667901-13-5
  • Molecular Weight:146.52 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zalutumumab
  • Experimental Validation Results for Zalutumumab
  • Experimental Validation Results for Zalutumumab
  • Zalutumumab Chemical Structure
    Zalutumumab Chemical Structure
CAS No.: 667901-13-5
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Zalutumumab:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

All EGFR Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human EGFR Protein (ECD, His Tag) can bind Zalutumumab. The EC50 for this effect is 5.92 ng/mL.

  • 1/16

    Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Zalutumumab (anti-ERBB1/EGFR/HER1) (HY-P99155). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1(K214R) kappa (HY-P99995). Black-Unlabelled control, cells without incubation with primary antibody.

  • Zalutumumab Chemical Structure
    1/16
  • Zalutumumab
  • Immobilized Human EGFR Protein (ECD, His Tag) can bind Zalutumumab. The EC50 for this effect is 5.92 ng/mL.
  • Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Zalutumumab (anti-ERBB1/EGFR/HER1) (HY-P99155). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1(K214R) kappa (HY-P99995). Black-Unlabelled control, cells without incubation with primary antibody.