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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
human GIPR
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "human GIPR" in MCE Product Catalog:
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide sodium exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide sodium can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
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Cat. No.: HY-164535
CAS No.: 2887445-76-1
Synonyms: AMG 133
Cat. No.: HY-P990047
CAS No.: 2761478-99-1
Synonyms: AMG133 antibody
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Cat. No.: HY-P10031
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Cat. No.: HY-P3584A
Synonyms: (Pro3) Gastric Inhibitory Peptide, human TFA
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Cat. No.: HY-P10031A
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Cat. No.: HY-P3584
CAS No.: 299898-52-5
Synonyms: (Pro3) Gastric Inhibitory Peptide, human
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Cat. No.: HY-P11237
CAS No.: 2869147-44-2
Synonyms: CT-388
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Cat. No.: HY-P3506CP
CAS No.: 2381089-83-2
Synonyms: LY3437943 (crude)
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Cat. No.: HY-RS05437
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GIPR Human Pre-designed siRNA Set A contains three designed siRNAs for GIPR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1731CP
CAS No.: 2023788-19-2
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Tirzepatide (LY3298176) (crude) is the crude form of Tirzepatide (HY-P1731).Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
Cat. No.: HY-171302
CAS No.: 2766799-78-2
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GLP-1R/GIPR agonist-2 is a GIPR agonist. GLP-1R/GIPR agonist-2 potentiates GIP(1-42)-induced intracellular cAMP production in cells expressing human GIPR. GLP-1R/GIPR agonist-2 can be used for the research of type II diabetes mellitus .
Cat. No.: HY-P702285
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide Receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide Receptor
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Cat. No.: HY-P702800
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide Receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide Receptor
Cat. No.: HY-P703990
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide Receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide Receptor
Cat. No.: HY-P703982
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory Polypeptide Receptor; PGQTL2; Glucose-Dependent Insulinotropic Polypeptide Receptor
Cat. No.: HY-182580
CAS No.: 1942922-78-2
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HBK001 is an orally active and selective dual GPR119 agonist and DPP-IV inhibitor. HBK001 triggers cAMP production, PKA activation, CREB phosphorylation, glucose-stimulated insulin secretion, plasma incretin elevation, β-cell proliferation, and β-cell function gene up-regulation. HBK001 reduces blood glucose, ameliorates hyperglycemia, improves glucose tolerance, and enhances islet morphology. HBK001 can be used for the research of type 2 diabetes mellitus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
