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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
human GLP-1R
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "human GLP-1R" in MCE Product Catalog:
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2 Cited Publications
Cat. No.: HY-P81160
Synonyms: Glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; GLP1R; GLP; GLP1R; Glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; GLP-1-R; GLP1R_human; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.
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2 Cited Publications
Cat. No.: HY-P700468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuGlucagon-like peptide 1 receptor/GLP1R, Fc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R
Cat. No.: HY-P3375
CAS No.: 2259884-03-0
Synonyms: IBI-362; LY-3305677; OXM-3
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Cat. No.: HY-164535
CAS No.: 2887445-76-1
Synonyms: AMG 133
Cat. No.: HY-P11274A
Synonyms: Amycretin sodium; NN 9487 sodium
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Cat. No.: HY-160734
CAS No.: 2685823-26-9
Synonyms: GSBR-1290
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Aleniglipron (GSBR-1290) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist, with an EC50 value of less than 0.1 nM in HDB cell lines in cAMP stimulation assays. Aleniglipron selectively activates the Gαs-cAMP signaling pathway of GLP-1R without β-arrestin recruitment. Aleniglipron induces insulin release, promotes glucose clearance, reduces food intake and decreases body weight. Aleniglipron is applicable to research related to type 2 diabetes and obesity .
Cat. No.: HY-175701
CAS No.: 2810808-95-6
Synonyms: RO7795081; RG6652
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CT-996 is an orally active GLP-1RA agonist with an EC50 of 0.49 nM. CT-996 reduces the recruitment of β-arrestin and the internalization of GLP-1R. CT-996 suppresses postprandial blood glucose in mice expressing human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkeys during intravenous glucose challenge. CT-996 can be used for the research of type 2 diabetes (T2D) and obesity .
Cat. No.: HY-P3375A
Synonyms: IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA
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Cat. No.: HY-P10031
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Cat. No.: HY-P990013
CAS No.: 2642374-02-3
Synonyms: Glutazumab; GMA-102; GMA-105
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V-0219 is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 potentiates glucose-dependent insulin secretion. V-0219 improves glucose handling in normal and diabetic rodents. V-0219 can be used for the research of obesity-associated diabetes .
Cat. No.: HY-N2452
CAS No.: 956103-79-0
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Cat. No.: HY-RS05490
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GLP1R Human Pre-designed siRNA Set A contains three designed siRNAs for GLP1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991099
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V-0219 hydrochloride is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 hydrochloride potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 hydrochloride potentiates glucose-dependent insulin secretion. V-0219 hydrochloride improves glucose handling in normal and diabetic rodents. V-0219 hydrochloride can be used for the research of obesity-associated diabetes .
Cat. No.: HY-P11043
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Cat. No.: HY-P10031A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
